Prospective Non-Interventional Study Comparing Standard of Care Osimertinib +/- Chemotherapy for EGFR-Mutated Non-Small Cell Lung Cancer (NSCLC) Patients
Prospective Non-Interventional Study Comparing Standard of Care Osimertinib +/- Chemotherapy for EGFR-Mutated Non-Small Cell Lung Cancer (NSCLC) Patients
The goal of the study is to collect data on patients treated outside of a clinical trial (in routine clinical practice) with standard of care osimertinib with or without chemotherapy in Epidermal Growth Factor Receptor (EGFR)-mutant Non-Small Cell Lung Cancer (NSCLC) to better understand the safety and effectiveness of these standard of care regimens.
This study tests the feasibility of using real-world data collection through the recruitment of well-characterized patients into a registry, spanning academic and community practice sites to determine patient outcomes in all-comers. The scientific community would further benefit from a greater understanding of the safety and effectiveness of newly approved therapies prescribed in routine clinical practice.
Non-interventional (observational) study with 250 participants per exposure group (maximum accrual up to 538 total participants) comparing outcomes in patients with EGFR-mutated NSCLC, not being treated in a clinical trial but receiving standard of care osimertinib +/- chemotherapy.
The treating physician determines whether a patient will receive standard of care single agent osimertinib or osimertinib with chemotherapy and the planned treatment is recorded at registration.
Clinical/Imaging assessments will be per the treating physician.
Inclusion Criteria:
PrE1702@precogllc.org215-439-2294
Birmingham, Alabama 35294, United States
jpknapp@uabmc.edu205-962-6860
Hinesville, Georgia 31313, United States
Jesup, Georgia 31545, United States
Savannah, Georgia 31405, United States
Baltimore, Maryland 21201, United States
Maple Grove, Minnesota 55369, United States
Columbus, Mississippi 39705, United States
New Albany, Mississippi 38652, United States
Oxford, Mississippi 38655, United States
Southhaven, Mississippi 38671, United States
Morristown, New Jersey 07960, United States
Pinehurst, North Carolina 28374, United States
Hazleton, Pennsylvania 18201, United States
Wilkes-Barre, Pennsylvania 18711, United States
Bluffton, South Carolina 29910, United States
Hilton Head Island, South Carolina 29926, United States
Collierville, Tennessee 38017, United States
Memphis, Tennessee 38120, United States
Janesville, Wisconsin 53548, United States
Summit, Wisconsin 53066, United States
angela.timler@aah.org262-434-8866
billy.cater@mercy.net417-314-7490
billy.cater@mercy.net417-314-7490
jennifer.goudy@bmhcc.org901-226-3631
sghandi@stanford.edu650-723-0503
sghandi@stanford.edu650-723-0503
sghandi@stanford.edu650-723-0503
suzanne.brennan@johnmuirhealth.com925-692-5603
adrianna_davis@bayhealth.org302-744-7994
adrianna_davis@bayhealth.org302-744-7994
atariq6@jhmi.edu202-660-5712
lamakerk@sjchs.org912-819-6204
lamaker@sjchs.org912-819-6204
lamakerk@sjchs.org912-819-6204
olga.marquis@aah.org847-620-7153
danielle.kline@northwestern.edu312-695-1352
nbatra@cookcountyhhs.org312-864-7254
vanessa.vazquez@aah.org773-296-9842
christabel.yawson@northwestern.edu630-315-8902
elizabeth.marston@northwestern.edu630-938-2190
jessicamarie.mazza@northwestern.edu224-271-6339
jessicamarie.mazza@northwestern.edu224-271-6339
frederick.betts@aah.org708-575-4414
jessicamarie.mazza@northwestern.edu224-271-6339
mary.baker@carle.com217-326-4506
kathleen.munoz@aah.org708-684-4694
delaine.bartley@northwestern.edu708-923-5249
kristina.dorsen-dziwulski@aah.org847-723-8246
mary.baker@carle.com217-326-4506
melissa.bergmann@nm.org630-938-2064
kaylee.martin@umm.edu410-328-2288
sschmitt@gbmc.org443-849-3285
priscilla.veera@tuftsmedicine.org617-636-8382
priscilla.veera@tuftsmedicine.org617-636-8382
priscilla.veera@tuftsmedicine.org617-636-8382
justin.eklund@parknicollet.com952-993-1555
justin.eklund@parknicollet.com952-993-1555
justin.eklund@parknicollet.com952-993-1555
justin.eklund@parknicollet.com952-993-1555
justin.eklund@parknicollet.com952-993-1555
justin.eklund@parknicollet.com952-993-1555
justin.eklund@parknicollet.com952-993-1555
justin.eklund@parknicollet.com952-993-1555
justin.eklund@parknicollet.com952-993-1555
justin.eklund@parknicollet.com952-993-1555
justin.eklund@parknicollet.com952-993-1555
justin.eklund@parknicollet.com952-993-1555
justin.eklund@parknicollet.com952-993-1555
justin.eklund@parknicollet.com952-993-1555
justin.eklund@parknicollet.com952-993-1555
justin.eklund@parknicollet.com952-993-1555
justin.eklund@parknicollet.com952-993-1555
justin.eklund@parknicollet.com952-993-1555
justin.eklund@parknicollet.com952-993-1555
justin.eklund@parknicollet.com952-993-1555
justin.eklund@parknicollet.com952-993-1555
justin.eklund@parknicollet.com952-993-1555
justin.eklund@parknicollet.com952-993-1555
justin.eklund@parknicollet.com952-993-1555
jennifer.goudy@bmhcc.org901-226-3631
jennifer.goudy@bmhcc.org901-226-3631
jennifer.goudy@bmhcc.org901-226-3631
jennifer.goudy@bmhcc.org901-226-3631
jennifer.goudy@bmhcc.org901-226-3631
jennifer.goudy@bmhcc.org901-226-3631
jennifer.goudy@bmhcc.org901-226-3631
cynthia.meyer@mercy.net417-556-3980
shelby.bradford@mercy.net417-458-6326
jennifer.hylton@mercy.net417-820-9748
danielle.werle@mercy.net314-525-6042
emily.hoven@mercy.net314-251-7061
kkrayer@virtua.org856-247-7397
maimanivanh.phiakhamta@atlantichealth.org973-971-6328
maimanivanh.phiakhamta@atlantichealth.org973-971-6328
pb731@cinj.rutgers.edu732-395-8823
kevans2@valleyhealth.com201-634-5691
lauren.leva@jefferson.edu215-481-6684
maimanivanh.phiakhamta@atlantichealth.org973-971-6328
kkrayer@virtua.org856-247-7397
sherly.jacob-perez@chsli.org516-563-7176
ashah1@montefiore.org718-862-8840 ext. 436
alarawir@upstate.edu315-464-6074
yeng@montefiore.or718-405-8516
Joni.Langhorn@chsli.org631-417-8630
robyn.bryson@unchealth.unc.edu828-694-8603
tpthompson@firsthealth.org910-715-4434
carla.larch@aultman.com330-363-1250
lahalsey@premierhealth.com937-438-7819
kmpugh@premierhealth.com937-734-5972
eecebelak@premierhealth.com513-974-5674
lmharrall@premierhealth.com937-569-7529
pmberhow@premierhealth.com937-440-4829
marian.nolen@mercy.net405-755-1515
alhuttenstine@geisinger.edu570-214-2850
alhuttenstine@geisinger.edu570-214-2850
alhuttenstine@geisinger.edu570-214-2850
alhuttenstine@geisinger.edu570-214-2850
burrellje@mlhs.org484-476-2649
daniel.huth@pennmedicine.upenn.edu541-778-0331
lauren.leva@jefferson.edu215-481-6684
lauren.leva@jefferson.edu215-481-6684
lauren.leva@jefferson.edu215-481-6684
david.anderson@ahn.org412-578-1342
alhuttenstine@geisinger.edu570-214-2850
alhuttenstine@geisinger.edu570-214-2850
alhuttenstine@geisinger.edu570-214-2850
alhuttenstine@geisinger.edu570-214-2850
lauren.leva@jefferson.edu215-481-6684
lamaker@sjchs.org912-819-6204
lamaker@sjchs.org912-819-6204
jennifer.goudy@bmhcc.org901-226-3631
jennifer.goudy@bmhcc.org901-226-3631
jennifer.goudy@bmhcc.org901-226-3631
j.whisenant@vumc.org704-450-0147
claudia.sanchezlucas@UTSouthwestern.edu214-648-5797
lreynold01@jpshealth.org817-702-0907
matthias.weiss@thedacare.org920-354-3604
matthias.weiss@thedacare.org920-354-3604
matthias.weiss@thedacare.org920-354-3604
haley.ravenscraft@aah.org262-971-9208
starkita.purdle@aah.org414-489-5276
pamela.bohachek@aah.org262-532-8499
kyle.crivello@aah.org262-329-5075
sarah.peterson@aah.org920-288-4311
ahuppert@mhemail.org608-756-6695
michele.ambrosius@aah.org262-857-5696
klvictor@gundersenhealth.org608-775-0495
lruelle@wisc.edu608-265-7983
tesmer.brooke@marshfieldresearch.org715-221-7330
kyle.crivello@aah.org262-329-5075
Kristina.Dorsen-Dziwulski@aah.org847-723-8246
wendy.cooper@aah.org414-385-5845
christian.donahoe@aah.org414-328-6724
kevin.morrow@aah.org414-219-5813
matthias.weiss@thedacare.org920-354-3604
matthias.weiss@thedacare.org920-354-3604
matthias.weiss@thedacare.org920-354-3604
deana.vandebrink@aah.org920-456-7687
michelle.ambrosius@aah.org262-884-8352
matthias.weiss@thedacare.org920-354-3604
mary.theodoroff@aah.org920-435-3540
heather.fabian@aah.org920-451-5039
dawn.minikel@phci.org262-928-3447
matthias.weiss@thedacare.org920-354-3604
pamela.bohachek@aah.org262-532-8499