Online Mindfulness-based Stress Reduction for Patients Receiving Chemotherapy

Online Mindfulness-based Stress Reduction Intervention for Patients With Breast Cancer Receiving Chemotherapy

The goal of this prospective, waitlist-controlled, 1:1 randomized study is to evaluate if an online mindfulness-based intervention (MBI) reduces treatment-related stress levels among patients with breast cancer receiving chemotherapy.

The main questions it aims to answer are:

• Does an online MBI intervention reduce stress levels (measured through the Perceived Stress Scale) among participants?
• Does an online MBI intervention reduce anxiety, depression, insomnia, fatigue, nausea, diarrhea, constipation, pain, and peripheral neuropathy (measured through the PRO-CTCAE of the National Cancer Institute) among participants?

Researchers will compare the online MBI to no intervention to see if online MBI reduces treatment-related stress.

Participants will:

• Participate in an online MBI or no intervention for 6 weeks
• Answer the study surveys at baseline, 7 weeks, and 11 weeks of follow-up

Inclusion Criteria:

• Female sex
• Age ≥18 years
• Diagnosis of non-metastatic breast cancer
• Treatment with neoadjuvant or adjuvant chemotherapy or plan to start chemotherapy in <4 weeks
• Internet access at home or in their mobile phone
• Availability to participate in the online MBI for 6 weeks
• Availability to answer the study surveys
• Provision of signed informed consent

Exclusion Criteria:

• Disease recurrence
• Current meditation or mindfulness practice
• Inability to read or write