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The main hypothesis is that autonomic dysfunction cannot improve among patients reaching end-stage heart failure. To evaluate this, patients admitted with acute decompensated heart failure in Bispebjerg hospital, and history one or more admissions with the same condition within the prior year, will undergo repeated brief heart monitoring (10 min). Baseline recordings (at admission) will be compared with equivalent measurements before discharge to explore whether heart rate variability increases. Patients will be followed for six months after discharge from the hospital.
If the patient accepts to participate and signed the project informed consent, their clinical record will be followed until the last patient included has been followed for six months.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| heart monitoring | Diagnostic Test | individual comparison of heart rate variability at admission with a repeated measurement before discharge |
|
| Measure | Description | Time Frame |
|---|---|---|
| number of rehospitalizations | number of emergency rehospitalizations, classified according to:
| up to six months after discharge from index admission |
| Measure | Description | Time Frame |
|---|---|---|
| Heart rate Variability change from admission to discharge | Measurement of heart-rate oscillations over a short term (30 min) of continuous three-lead electrocardiogram recording divided into two time domains: Domain 10min: relaxed, supine position for 10 min Domain 30 min: comprising the first 10 min-domain in addition to stand-up and walking for 5 min, followed by sitting relaxed until completing 30 min recording in total |
| Measure | Description | Time Frame |
|---|---|---|
| Diastolic function | Measurement of changes diastolic function in right and left ventricle based on wavelet-ECG measurements | six months |
Inclusion Criteria:
Exclusion Criteria:
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Patients admitted to the hospital with acute decompensated heart failure, regardless of measured left ventricle ejection fraction.
Patients will be grouped according to rhythm: sinus rhythm and atrial fibrillation.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Helena Dominguez | Contact | 22989343 | mdom0002@regionh.dk |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cardiology department Y, Bispebjerg-Frederiksberg Hospital | Recruiting | Frederiksberg | 2000 | Denmark |
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| ID | Term |
|---|---|
| D006333 | Heart Failure |
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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| ID | Term |
|---|---|
| D000070276 | Heart Rate Determination |
| ID | Term |
|---|---|
| D006334 | Heart Function Tests |
| D003935 | Diagnostic Techniques, Cardiovascular |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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| repeated measurement at baseline (within 48h from time of index admission) and before discharge (estimated one week on average from index admission) |
| D010808 | Physical Examination |