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Varicose veins are irreversible and abnormal enlargement of the veins. These veins appear and there are curled swellings under the skin in the feet and legs. Complaints increase when standing and sitting for long periods. For varicose veins in the initial stages, medical treatment methods such as compression socks (elastic socks) and elevating the feet as much as possible can be tried. For widespread varicose veins in more advanced stages, invasive procedures such as sclerotherapy and endovascular ablation are performed. These procedures can be performed under local, spinal or general anesthesia.
Spinal anesthesia; It is a type of neuraxial type of regional anesthesia characterized by injecting local anesthetic drugs into the subarachnoid space alone or together with other drugs, resulting in temporary sensory block, motor block, and sympathetic block. The local anesthetic volume administered during spinal anesthesia may affect the anesthesia levels and discharge times of the patients. For varicose vein surgeries, low-dose local anesthetic is sufficient for spinal anesthesia and can also provide early discharge.
This study will compare the peri-operative effects of different doses of spinal anesthesia in patients undergoing varicose vein surgery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Spinal anesthesia with 4 mg bupivacaine | Active Comparator | After the patients are monitored, they will be placed in the lateral decubitus position. After appropriate field sterilization, patients will undergo unilateral spinal anesthesia with 4 mg bupivacaine. At the fifth minute after spinal anesthesia, patients will be placed in the supine position. |
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| Spinal anesthesia with 6 mg bupivacaine | Active Comparator | After the patients are monitored, they will be placed in the lateral decubitus position. After appropriate field sterilization, patients will undergo unilateral spinal anesthesia with 6 mg bupivacaine. At the fifth minute after spinal anesthesia, patients will be placed in the supine position. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| 4 mg bupivacaine | Procedure | Spinal anesthesia was applied to the patients with 4 mg bupivacaine in the lateral decubitus position. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Discharge time | The time (minutes) from the application of spinal anesthesia to the patients' discharge will be recorded as the discharge period. | On the operation day |
| Measure | Description | Time Frame |
|---|---|---|
| Motor block appearing time | Time (minutes) to complete motor block in the lower extremity after spinal anesthesia | On the operation day |
| Sensorial block appearing time | Time (minutes) to complete sensorial block in the lower extremity after spinal anesthesia |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ankara Etlik City Hospital | Yenimahalle | Ankara | 06170 | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41519711 | Derived | Sezgi A, Zengin M, Hekimoglu S, Taskir Turan M, Topcu I, Arik E, Cakmak EK, Ozdemir Sezgi ES, Kina SF, Ergil J. Different local anesthetic volumes for unilateral spinal anesthesia in varicose vein surgery prospective randomized clinical trial. BMC Anesthesiol. 2026 Jan 10;26(1):95. doi: 10.1186/s12871-026-03619-z. |
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| ID | Term |
|---|---|
| D002045 | Bupivacaine |
| ID | Term |
|---|---|
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 | Aniline Compounds |
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| 6 mg bupivacaine | Procedure | Spinal anesthesia was applied to the patients with 6 mg bupivacaine in the lateral decubitus position. |
|
| On the operation day |
| Motor block disappearing time | Time (minutes) to disappearance of complete motor block in the lower extremity after spinal anesthesia | On the operation day |
| Sensorial block disappearing time | Time (minutes) to disappearance of sensorial block in the lower extremity after spinal anesthesia | On the operation day |
| D000588 |
| Amines |