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Define the prevalence of fecal phage carriage in individuals with digestive symptoms (i) Determine the concentrations of infectious fecal phages in the stools of individuals with digestive symptoms (detection by culture)
(ii) Determine fecal phage genome concentrations in the stools of individuals with digestive symptoms (PCR detection)
(iii) Explore factors that could impact fecal phage carriage (patients with digestive symptoms vs. healthy individuals, immunocompromised patients vs. immunocompetent patients)
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| immunocompetent | immunocompetent patients with digestive symptoms (n=150) |
| |
| immunocompromised | immunocompromised patients with digestive symptoms (n=150) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| bacteriophage detection | Other | bacteriophage detection |
|
| Measure | Description | Time Frame |
|---|---|---|
| prevalence of faecal phage carriage | define the prevalence of faecal phage (coliphage) carriage in individuals presenting with digestive symptoms. | baseline |
| Measure | Description | Time Frame |
|---|---|---|
| concentrations of infectious fecal phages | Determine the concentrations of infectious fecal phages in the stools of individuals with digestive symptoms (detection by culture) | baseline |
| fecal phage genome concentrations |
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Inclusion Criteria:
Exclusion Criteria:
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patients hospitalized at the CHRU de Nancy with digestive symptoms requiring microbiological stool analysis
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Cédric Hartard | Contact | 0383153046 | c.hartard@chru-nancy.fr |
| Name | Affiliation | Role |
|---|---|---|
| Cédric Hartard | CHRU Nancy | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHRU Nancy | Nancy | 54000 | France |
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| ID | Term |
|---|---|
| D005759 | Gastroenteritis |
| ID | Term |
|---|---|
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
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stool sample
determine fecal phage genome concentrations in the stools of individuals with digestive symptoms (PCR detection)
| baseline |