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The aim of this study is to identify risk factors associated with sepsis and to construct a predictive model for sepsis. This will provide an objective theoretical and empirical foundation for the diagnosis, assessment, and management of sepsis in our country.The primary questions addressed are:
What are the risk factors for the development of sepsis? How do we improve the prognosis of sepsis?
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Sepsis Group |
| ||
| Non-Sepsis Group |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Tumor Necrosis Factor | Other | This study is a retrospective observational study, with Tumor Necrosis Factor being one of the exposure factors under investigation. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Sepsis | A rapid increase of 2 or more points points in the Sequential Organ Failure Assessment (SOFA) score after patient infection.SOFA score, which ranges from a minimum of 2 to a maximum of 15, indicates a worse outcome with higher scores. | 3 months |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with Infection or Suspected Infection
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Xiue Ye | Wenzhou | Zhejiang | 325000 | China | ||
| The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, |
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| ID | Term |
|---|---|
| D018805 | Sepsis |
| ID | Term |
|---|---|
| D007239 | Infections |
| D018746 | Systemic Inflammatory Response Syndrome |
| D007249 | Inflammation |
| D010335 | Pathologic Processes |
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| ID | Term |
|---|---|
| D014409 | Tumor Necrosis Factor-alpha |
| D018664 | Interleukin-12 |
| D020382 | Interleukin-18 |
| D003176 | Complement C3 |
| D003182 | Complement C5 |
| ID | Term |
|---|---|
| D006023 | Glycoproteins |
| D006001 | Glycoconjugates |
| D002241 | Carbohydrates |
| D015846 | Monokines |
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| Interleukin-1β | Other | This study is a retrospective observational study, with Interleukin-1β being one of the exposure factors under investigation. |
|
| Interleukin-12 | Other | This study is a retrospective observational study, with Interleukin-12 being one of the exposure factors under investigation. |
|
| Interleukin-18 | Other | This study is a retrospective observational study, with Interleukin-18 being one of the exposure factors under investigation. |
|
| Complement C3 | Other | This study is a retrospective observational study, with Complement C3 being one of the exposure factors under investigation. |
|
| Complement C5 | Other | This study is a retrospective observational study, with Complement C5 being one of the exposure factors under investigation. |
|
| Wenzhou |
| Zhejiang |
| 325027 |
| China |
| D013568 |
| Pathological Conditions, Signs and Symptoms |
| D016207 |
| Cytokines |
| D036341 | Intercellular Signaling Peptides and Proteins |
| D010455 | Peptides |
| D000602 | Amino Acids, Peptides, and Proteins |
| D048069 | Tumor Necrosis Factors |
| D001798 | Blood Proteins |
| D011506 | Proteins |
| D001685 | Biological Factors |
| D007378 | Interleukins |
| D000209 | Acute-Phase Proteins |
| D003165 | Complement System Proteins |
| D007162 | Immunoproteins |