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Cognitive impairment is common in people who suffer from hypoxia. Acupuncture and related techniques can be used to improve hypoxia and treat cognitive impairment. In this trial the effect of transcutaneous electrical acupoint stimulation on cognitive impairment in people under hypoxia will be investigated.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| transcutaneous electrical acupoint stimulation | Experimental | Electrodes are placed at acupoints and connected to the stimulators. Electrical stimulation is given for 2 hours |
|
| Control | No Intervention | Electrodes are placed at acupoints but no electrical stimulation is given |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| transcutaneous electrical acupoint stimulation | Other | Electrodes are placed at acupoints and connected to the stimulator. Electrical stimulation is given for 2 hours. |
|
| Measure | Description | Time Frame |
|---|---|---|
| cognitive function measured by eye-tracking at 1 hour after hypoxia | 1 hour after hypoxia | |
| cognitive function measured by eye-tracking at 2 hours after hypoxia | 2 hours after hypoxia |
| Measure | Description | Time Frame |
|---|---|---|
| mean arterial blood pressure | starting from 10 minutes before hypoxia to 2 hours after hypoxia, every 5 minutes for 2 hours and 10 minutes | |
| heart rate | starting from 10 minutes before hypoxia to 2 hours after hypoxia, every 5 minutes for 2 hours and 10 minutes |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Zhihong Lu | Contact | +8613891975018 | deerlu23@163.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Xijing Hospital | Xi'an | Shaanxi | 710032 | China |
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| ID | Term |
|---|---|
| D000860 | Hypoxia |
| ID | Term |
|---|---|
| D012818 | Signs and Symptoms, Respiratory |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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The stimulator is put in an opaque box
| saturation of pulse oximetry | starting from 10 minutes before hypoxia to 2 hours after hypoxia, every 5 minutes for 2 hours and 10 minutes |
| Cerebral oxygen saturation | starting from 10 minutes before hypoxia to 2 hours after hypoxia, every 5 minutes for 2 hours and 10 minutes |
| total sleep time on the first day after hypoxia | the first day after hypoxia, in a total of 24 hours |
| sleep efficiency(%) on the first day after hypoxia | sleep efficiency=total sleep time/total recording time | the first day after hypoxia, in a total of 24 hours |
| number of awake on the first day after hypoxia | the first day after hypoxia, in a total of 24 hours |
| time of awake on the first day after hypoxia | the first day after hypoxia, in a total of 24 hours |