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This study is a randomized, double-blind, placebo-controlled study of N=20 active men and women. This study to assess the effect of a novel dietary supplement on improving nutrient gaps and the gut microbiome.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Placebo | Placebo Comparator | Maltodextrin + Flavoring |
|
| AG1 - Nutritional Supplement | Experimental | A foundational nutritional supplement consisting of vitamins, minerals, probiotics, prebiotics, and whole food ingredients |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| AG1 - Nutritional Supplement | Dietary Supplement | A foundational nutritional supplement consisting of vitamins, minerals, probiotics, prebiotics, and whole food ingredients |
|
| Measure | Description | Time Frame |
|---|---|---|
| Gut Microbiome | Examine changes in the gut microbiome via fecal polar metabolomics measured by LC/MS | 14 days |
| Nutrient Gaps | Assess nutrient gaps by dietary record assessment utilizing The Automated Self-Administered 24-hour (ASA24®) Dietary Assessment Tool | 14 days |
| Measure | Description | Time Frame |
|---|---|---|
| Exploratory Digestive Measures | A Digestive Quality of Life Questionnaire (DQLQ) will be utilized to assess the effect of the interventions on participant's digestive health. Scores range from 0 to 9 with a higher score indicating worse digestion associated with quality of life | 14 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hofstra University | Hempstead | New York | 11549 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41988471 | Derived | Gonzalez AM, Townsend JR, Sapp PA, Edwards C, Kirby TO, Wright J, Lamendella R, Esposito R. Effect of AG1(R) supplementation on nutritional adequacy and gut microbial composition in trained adults. Front Nutr. 2026 Mar 31;13:1783951. doi: 10.3389/fnut.2026.1783951. eCollection 2026. |
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| ID | Term |
|---|---|
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D001519 | Behavior |
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Randomized, Double-Blind, Placebo Controlled Design
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| Placebo | Dietary Supplement | Maltodextrin placebo |
|