To date, there are no methods for assessing the risk of oral developmental defects that could predict long-term adverse effects in childhood cancer survivors. Having such a method at our disposal would enable us to better assess the risk to develop those defects and will help us provide new prevention and treatment strategies to ensure a healthy oral development.

The aims of this study are :

• Assess the caries risk in childhood cancer survivors compared with a control group.
• Assess the dental development defects risk in childhood cancer survivors compared with a control group.

This will be an international study comparing the Childhood Cancer Survivors (CCS) and a control group.

A questionnaire will be provided to the patients to gather information. A standard of care dental examination will then take place in a dental office in the Cliniques Universitaires Saint-Luc. We also collect medical data to complete the files.

Inclusion Criteria:

• age below 10 at cancer diagnosis (for the CCS group).
• Chemotherapy must have been used to treat the patient (For the CCS group).
• The patient is 12 years old or older at the time of the follow-up appointment of the present study

Exclusion Criteria:

• A patient who was diagnosed and treated after 10 years old.
• Patient below 12 years old at time of study recruitment
• Patients with syndrome or diseases that involve teeth impairment*
• Pregnant patient
• Refusal or inaptitude to undergo dental and radiographic examination