crohn's disease patients who present by intestinal perforation as the first presentation are hard to deal with. Surgical techniques as anastmosis or diversion stoma and active course of the disease may greatly affect the quality of life. In post-operative period, is the priority to avoid the post operative complications and to improve surgical outcomes or to stop active course of the disease and to induce remission?. So, those patients were classified into two groups. one group received biological therapy early post operative and the other group received it 2 or 3 months later after surgery and the investigators will compare results between the two groups.

Inclusion Criteria:

• patients at or above 18 years old
• patients with perforated bowel diagnosed as Crohn's disease at presentation underwent surgery

Exclusion Criteria:

• patients less than 18 years old
• well known Crohn's disease patients on medical treatment
• associated bowel disease as malignancy and diverticulosis.

patients with Crohn's disease presented with bowel perforation

data will be available on demand by contacting the principle investigator