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A study measuring rewards sensitivity in individuals with acquired brain injury at an acute rehabilitation level.
Individuals in acute rehabilitation following acquired brain injury journal (ABI) and aged-matched, non-injured controls will be recruited for this study.
Testing sessions will take place in a private treatment room at the Shirley Ryan AbilityLab and required 45 minutes to complete. Upon entering the room, participants will be greeted, electrodes placed on the participant's fingers to record their electrodermal activity, and participants will provide demographic information. Participants will then be instructed about how to respond on the Cued Reinforcement Response Time task (CRRT, see description below), and complete the task on a laptop computer while their electrodermal activity is being recorded. In this task, they are instructed to respond as quickly and accurately as possible, and will be informed that they will receive a monetary reward based on their accuracy at the completion of the task. Finally, participants will complete 3 self-report measures: (1) explicit level of motivation was measured in a post-study survey which included two items from the Sensitivity to Punishment and Sensitivity to Reward Questionnaire, (SPSRQ); (2) Reward sensitivity was evaluated using the Reward Responsiveness Scale , and (3) depression was evaluated using the Patient Health Questionnaire (PHQ-8) survey. At the end of the session, the electrodes will be removed, and participants will be debriefed and provided their monetary reward
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Individuals with Acquired Brain Injury | Experimental | Measuring the effect of three different types of rewards (one dollar, one penny, and no reward) on performance in a cognitive test. |
|
| Non-impaired controls | Other | Measuring the effect of three different types of rewards (one dollar, one penny, and no reward) on performance in a cognitive test. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Type of reward presented | Behavioral | Three different types of rewards were presented to both groups during the computerized task: one dollar, one penny, and no reward. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Performance on a Cued Response Reaction Time Task, in each of the three rewards conditions (Dollar, Penny, No reward) | Accuracy (percentage of correct responses) in a Cued Response Reaction task | 15 minutes |
| Performance on a Cued Response Reaction Time Task, in each of the three rewards conditions (Dollar, Penny, No reward) | Response time (time in milliseconds) in a Cued Response Reaction task | 15 minutes |
| Electrodermal activity (EDA) before, during and after the Cued Response Reaction task | Number of skin conductance responses (SCRs) before, during and after the task | 30 minutes |
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Inclusion Criteria:
Individuals with ABI
Healthy participants
Exclusion Criteria:
Individuals with ABI
Healthy Participants
• history of significant cerebrovascular or neurological disease including (but not limited to) meningitis, epilepsy and/or seizures, stroke, tumor, multiple sclerosis, meningitis, mental retardation, dementia.
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| Name | Affiliation | Role |
|---|---|---|
| Shira Cohen-Zimerman, PhD | Shirley Ryan AbilityLab | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Shirley Ryan AbilityLab | Chicago | Illinois | 60611 | United States |
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| ID | Term |
|---|---|
| D001930 | Brain Injuries |
| ID | Term |
|---|---|
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D006259 | Craniocerebral Trauma |
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2X3 non-randomized, within-participant design.
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| D020196 | Trauma, Nervous System |
| D014947 | Wounds and Injuries |