The Effects of Periodontal Therapy on Gingival Crevicular Fluid NLRP3,Caspase-1,IL-1β Levels in Children With Gingivitis

The Effects of Periodontal Therapy on Gingival Crevicular Fluid NLRP3,Caspase-1,IL-1β Levels in Children With Gingivitis

This study aims to determine the levels of NLRP3, caspase-1 and IL-1β concentrations in the gingival crevicular fluid of paediatric patients with gingivitis and their changes after periodontal treatment.

After being informed about the study and potential risks, necessary periodontal measurements will be performed and gingival crevicular fluid will be collected from all patients who gave written informed consent, and patients with gingivitis will be followed up on the 7th and 30th day after periodontal treatment.

Inclusion Criteria:

Inclusion criteria for the group with gingivitis;

• Systemically healthy
• 11-14 years old
• Permanent dentition
• No need for endodontic and restorative treatment
• Gingivitis with gingivitis
• Have verbally and in writing agreed to participate in the study and are willing to attend follow-up appointments regularly participants will be included in the study.

Inclusion criteria for the healthy group;

• Systemically healthy
• 11-14 years old
• Permanent dentition
• No need for endodontic and restorative treatment
• Periodontally healthy
• Have verbally and in writing agreed to participate in the study and are willing to attend follow-up appointments regularly participants will be included in the study.

Exclusion Criteria

• In need of endodontic and restorative treatment
• Systemically unhealthy
• Patients who do not give verbal or written consent