Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The pH of saliva can be acidic or alkaline; When it is acidic, the tooth enamel is demineralized, that is, weakened. Additionally, bacteria in the mouth can increase and cause infections such as cavities. This occurs when we consume sugary or fermented drinks, such as soda or beer.
The intention of the research team is to give some of these drinks to the study participants and verify the decrease in salivary pH. Next, a group of people will be asked to kiss their partner on the mouth, and then the pH will be measured again to see if it increases, that is, if it stops being acidic faster than in the group that did not kiss.
The aim is to demonstrate that kissing on the mouth between two people can protect teeth from cavities by rapidly increasing the pH of saliva after it has decreased to become acidic.
The goal of this intervention study will be to determine if oral kissing between two people can increase salivary pH more quickly after drinking artificial juices, soft drinks, or (non-alcoholic) beers. It will also be studied whether the pH restoration time is faster when only one person kisses one of the named drinks or when both people do it. The main questions that are intended to be answered are the following:
Saliva pH measurements will be performed, after initiation and consumption of the drinks, every 5 minutes for up to 40 minutes. That is, until the restoration of salivary pH is ensured in all groups.
Participants:
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control | No Intervention | The couples in the control group will not kiss; they will only wait for the salivary pH to neutralize physiologically. | |
| Only one person consumes the drink | Experimental | the group in which only one person in the couple consumes the sugary or fermented drink and they kiss |
|
| Both people consume the drink | Experimental | In this group, both people will consume the drinks and then kiss. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Kiss | Other | Participants will kiss with their partners for 40 seconds. The kiss will be on the mouth. |
|
| Measure | Description | Time Frame |
|---|---|---|
| salivary pH | It is expected to measure the progressive increase in pH until reaching a neutral point, which occurs physiologically between 30 to 40 minutes, and compare the time spent by the control group with that of the experimental group. Measurements will be taken every 5 minutes from the kiss, which will last 40 seconds. In total, there will be 8 measurements, not counting the initial one for surveying the baseline. The measurement will be carried out with a calibrated pH meter. People will be asked to drool into a test tube | In a period of every 5 minutes, until reaching 40 minutes, which is the time in which physiologically the pH of the saliva is neutralized. |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| School of Dentistry of the Catholic University Santiago de Guayaquil | Guayaquil | Guayas | 17-11-5058 | Ecuador |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30914852 | Background | Uma E, Theng KS, Yi LLH, Yun LH, Varghese E, Soe HHK. Comparison of Salivary pH Changes after Consumption of Two Sweetened Malaysian Local Drinks among Individuals with Low Caries Experience: A Pilot Study. Malays J Med Sci. 2018 Jul;25(4):100-111. doi: 10.21315/mjms2018.25.4.10. Epub 2018 Aug 30. | |
| 40674724 | Derived |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D003731 | Dental Caries |
| D017001 | Tooth Demineralization |
| ID | Term |
|---|---|
| D014076 | Tooth Diseases |
| D009057 | Stomatognathic Diseases |
Not provided
Not provided
| ID | Term |
|---|---|
| D059648 | Kisspeptins |
| ID | Term |
|---|---|
| D036341 | Intercellular Signaling Peptides and Proteins |
| D010455 | Peptides |
| D000602 | Amino Acids, Peptides, and Proteins |
| D009479 | Neuropeptides |
Not provided
Not provided
Couples were randomized to one of three parallel study arms: control (no kissing), Experimental Group 1 (one member of the couple consumed the beverage followed by kissing), and Experimental Group 2 (both members of the couple consumed the beverage followed by kissing). After allocation, one participant per couple was randomly selected for repeated salivary pH measurement and analysis. Each selected participant was scheduled to complete three weekly beverage sessions involving Coca-Cola, Cifrut, and non-alcoholic beer.
Not provided
Not provided
Not provided
Not provided
| Armijos Briones M, Aguila Gaibor M, Bermudez Velasquez A. Kissing as a Protective Factor Against Decreased Salivary pH: Protocol for a Randomized Clinical Trial. JMIR Res Protoc. 2025 Jul 17;14:e65253. doi: 10.2196/65253. |
| D025521 | Tumor Suppressor Proteins |
| D009363 | Neoplasm Proteins |
| D011506 | Proteins |