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Purpose - Bypass grafting is the gold standard for severe coronary disease, yet most repeat revascularizations target previously grafted territories. External stenting of saphenous vein grafts, the most frequently used bypass conduit, has been shown to minimize disease markers. This study evaluates clinical outcomes of external stenting in real world routine practice.
Methods - Three centers enrolled a prospective real-world cohort of external- stenting- enhanced CABG patients. All patients received an internal mammary artery graft to the left anterior descending artery and additional arterial and/or venous grafts. One or more venous grafts were externally stented. Choice of conduits, use of cardiopulmonary bypass, and vein harvesting technique were performed according to the routine practice of each surgeon.
All patients were prescribed standard of care medication and were followed via on site visits or phone interviews for major adverse myocardial and cerebral effects.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| VEST | Device | External MEsh Support for safein vein |
| Measure | Description | Time Frame |
|---|---|---|
| Re-rivascularization | Number of PCI or re-CABG performed, stratified by target site | Up to 7 years |
| MACCE | Major adverse cardiac and cerebrovascular events | Up to 7 years |
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Inclusion Criteria:
Exclusion Criteria:
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All comers for CABG with at least one vessel treated with VESTed Vein
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| Name | Affiliation | Role |
|---|---|---|
| Luca We | European Hospital - Rome | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Medical University of Vienna | Vienna | Austria | ||||
| Cardiochirurgia European Hospital |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30767438 | Background | Sandner S, Angleitner P, Laufer G, Zimpfer D. External stent (VEST) for saphenous vein grafts in coronary artery bypass grafting. Multimed Man Cardiothorac Surg. 2019 Feb 1;2019. doi: 10.1510/mmcts.2019.007. | |
| 33845865 | Result | Weltert LP, Audisio K, Bellisaro A, Bardi G, Flocco R, De Paulis R, Centofanti P. External stenting of vein grafts in coronary artery bypass grating: interim results from a two centers prospective study. J Cardiothorac Surg. 2021 Apr 12;16(1):74. doi: 10.1186/s13019-021-01406-0. |
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| Rome |
| 00152 |
| Italy |
| Mauriziano Hospital | Turin | Italy |
| 35312782 | Result | Sandner SE, Donovan TJ, Edelstein S, Puskas JD, Angleitner P, Krasopoulos G, Channon K, Gehrig T, Rajakaruna C, Ladyshenskij L, De Silva R, Bonaros N, Bolotin G, Jacobs S, Thielmann M, Choi YH, Ohri S, Lipey A, Friedrich I, Taggart DP. Effects of the harvesting technique and external stenting on progression of vein graft disease 2 years after coronary artery bypass. Eur J Cardiothorac Surg. 2022 Jun 15;62(1):ezac045. doi: 10.1093/ejcts/ezac045. |