Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
This study aims to assess the effect the intraligamentary injection of Diclofenac Potassium versus Articaine 4% on the anaesthetic efficacy & intensity of intraoperative & postoperative pain during single visit root canal treatment in patients with symptomatic irreversible pulpitis in mandibular molar teeth
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Diclofenac Potassium | Experimental | 0.4 ml diclofena potassium injection 75mg/3ml drug used as Supplemental intraligamentary injection |
|
| Articaine Anaesthetic solution | Active Comparator | Articaine 4% with (1:100,000 Epinephrine) local anesthetic solution will be used as intraligamentary injection, |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Diclofenac Potassium | Drug | NSAID |
|
| Measure | Description | Time Frame |
|---|---|---|
| Efficacy of local anesthesia | using Heft parker Visual Analogue scale Binary where success is defined as no pain or faint/weak /mild pain<55 mm). if >55 defined as failure | intraoperative ( access cavity preparation & instrumentation ) during root canal treatment |
| Measure | Description | Time Frame |
|---|---|---|
| Intensity of intraoperative pain | using Heft parker Visual analogue scale score ranges from on a 170-mm VAS line with the ends labeled "no pain" and "unbearable pain. .no pain (< 5 mm), mild pain (≥ 5 mm and ≤ 54 mm), Moderate pain (> 54 mm and < 114 mm), Severe pain (≥ 114 mm). | intraoperative ( access cavity preparation & instrumentation ) during root canal treatment |
Not provided
Inclusion Criteria:
Preoperative sharp pain, Absence or slight widening in the periodontal ligament (PDL), Vital response of pulp tissue to cold pulp test.
Exclusion Criteria:
Patients allergic to anesthetic solutions & other NSAIDs.
Pregnant or nursing females.
Patients having significant systemic disorder (ASA III or IV).
Gastrointestinal disorders.
If the initial diagnosis revealed pain in more than one tooth.
Hemostatic disorders or anti-coagulant therapy during the last month.
Consumption of opioid or non-opioid analgesics or NSAIDs during the last 12 hours before treatment.
Teeth that have:
i. Periodontal involvement (with pocket depth greater than 5mm, associated with swelling or fistulous tract, or greater than grade I mobility).
ii. No possible restorability. iii.Signs of pulpal necrosis; associated sinus tract or swelling.
-
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Mai Eldeeb, master | Contact | 01093738532 | mai.eldeeb@dentistry.cu.edu.eg |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Post-operative pain | using Heft parker Visual analogue scale on a 170-mm VAS line with the ends labeled "no pain" and "unbearable pain. .no pain (< 5 mm), mild pain (≥ 5 mm and ≤ 54 mm), Moderate pain (> 54 mm and < 114 mm), Severe pain (≥ 114 mm). | 6, 12, 24 and 48 hours post-operatively |
| Number of needed analgesic tablets in case of intolerable pain | by counting | Up to 2 days post operatively |
| ID | Term |
|---|---|
| D004008 | Diclofenac |
| ID | Term |
|---|---|
| D010648 | Phenylacetates |
| D000146 | Acids, Carbocyclic |
| D002264 | Carboxylic Acids |
| D009930 | Organic Chemicals |
Not provided
Not provided