Renalase(rs10887800) Genotyping & Leucocytes Telomere Len... | NCT06500351

Studies
Renalase(rs10887800) Genotyping & Leucocytes Telomere Length in Postpartum. Hypertension

NCT06500351

Sponsor

Sohag University

Status

Recruiting

Last Update Posted

Jul 16, 2024Actual

Enrollment

90Estimated

Phase

Not provided

Conditions

Renalase(rs10887800) Genotyping & Leucocytes Telomere Length in Patients With Postpartum Hypertension

Interventions

Not provided

Countries

Egypt

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Jul 2024

Overall Recruitment Status or Expanded Access Status

Recruiting

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Jun 25, 2024Actual

Primary Completion Date

Jun 25, 2025Estimated

Completion Date

Sep 1, 2025Estimated

First Submitted Date

Jul 8, 2024

First Submission Date that Met QC Criteria

Jul 8, 2024

First Posted Date

Jul 15, 2024Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Jul 12, 2024

Last Update Posted Date

Jul 16, 2024Actual

Oversight Module

Has Data Monitoring Committee (DMC)

Is FDA Regulated Drug

Is FDA Regulated Device

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

Not provided

FDAAA801 Violation

Not provided

Description Module

Brief Summary

This is an observertional study aimed at Study the association between Renalase(rs10887800) Genotyping & Leucocytes telomere length in patients with postpartum hypertension whether new onset( denovo) or persistent following pregnancy complicated by hypertension.

Detailed Description

Not provided

Design Module

Study Type

Observational

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Target Follow-Up Duration

Not provided

Phases

Not provided

Interventional Study Design

Allocation

Not provided

Intervention Model

Biospecimen

No data available

No data is available for this block.

Enrollment

90Estimated

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
denovo postpartum hypertension		females with new onset hypertension after delivary
persitant postpartum hypertension		females with preexisting hypertension or preeclampsia that persist after delivery
control		females with normal postpartum blood pressure

Interventions

Not provided

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Renalase(rs10887800) Genotyping	The presence of gene polymorphism whether homogenetic or heterogenetic	1 year

Secondary Outcomes

Measure	Description	Time Frame
Leucocytes telomere length	Measurement of the relative length of WBCs telomere in patints with postpartum hypertension	1 year

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

Patients who are18 years or above, and have a diagnosis of postpartum hypertension(regardless of where they received their antenatal care) attended to Sohag university hospitals

Exclusion Criteria:

All pregnant women with medical disorders in pregnancy other than Hypertensive disorders during pregnancy (e.g., sickle cell disease, heart disease, kidney and other connective tissues disorders) will be excluded from the study. Also we excluded measurements taken during scheduled or unscheduled surgical encounters given potential for interaction with anesthetic agents

Accepts Healthy Volunteers

Not provided

Sex

Female

Sex/Gender Based

Yes

Sex/Gender Description

only females are eligible for this study because of its relation to pregnancy.

Minimum Age

18 Years

Maximum Age

45 Years

Standard Ages

Adult

Study Population

Patients who were 18 years or above, and have a diagnosis of postpartum hypertension

Sampling Method

Probability Sample

Contacts/Locations Module

Central Contacts

Name	Role	Phone	Extension	Email
Amera Morad Foad, assistant professor	Contact	+201006591449		ameramoradfoad@gmail.com

Overall Officials

Name	Affiliation	Role
Amera Morad Foad, assistant professor	Sohag University	Principal Investigator

Locations

Facility	Status	City	State	ZIP	Country	Contacts
Sohag university hosoital	Recruiting	Sohag			Egypt