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Breast MRI has become an important tool for breast cancer detection and characterization.Contrast enhanced MRI(CE-MRI) is currently the most sensitive detection technique for diagnosis of breast cancer.
Most of the lesions that occur in the breast are benign lesions. It is important to recognize benign lesions and distinguish them from breast cancer.
Nowadays sonomammography still represents the primary imaging modality utilized for breast cancer screening and diagnosis.
Breast MRI has become an important tool for breast cancer detection and characterization.Contrast enhanced MRI(CE-MRI) is currently the most sensitive detection technique for diagnosis of breast cancer.Diffusion weighted imaging provides micro-structural informations regadrding the diffusion of the water molecules in the tissue cellularity and tissue structure by using the quantitive analysis with the apparent diffusion coefficient (ADC) values.
Using Diffusion weighted imaging (DWI) combined to MRI is helpful to distinguish malignant versus benign breast lesions and it also may reduce the number of unnecessarily breast biopsies.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| MRI device | Device | Standered breast coils with small field of veiw and thin sections will be used for the examinatio. MRI breast including Axial T1WI, T2WI Stir contrast DWI and Stir sagittal T1WI with contrast traction and subtraction |
| Measure | Description | Time Frame |
|---|---|---|
| Rate of correlated false positive results of MRI DWI for the lesion with the positive results by histopathology. | evaluation of the lesion with MRI DWI and histopathology for detect rate of false posive results | 6 months |
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Inclusion Criteria:
* Female gender
Exclusion Criteria:
Male gender
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Female gender
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Mennatullah A Ibrahim, resident | Contact | 01015003865 | menaashraf@med.sohag.edu.eg | |
| Medhat I Mohammed, professor | Contact | 01014005636 |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31554551 | Background | Stachs A, Stubert J, Reimer T, Hartmann S. Benign Breast Disease in Women. Dtsch Arztebl Int. 2019 Aug 9;116(33-34):565-574. doi: 10.3238/arztebl.2019.0565. | |
| 29455658 | Background | Butti R, Das S, Gunasekaran VP, Yadav AS, Kumar D, Kundu GC. Receptor tyrosine kinases (RTKs) in breast cancer: signaling, therapeutic implications and challenges. Mol Cancer. 2018 Feb 19;17(1):34. doi: 10.1186/s12943-018-0797-x. |
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| Type | Date | Date Unknown |
|---|---|---|
| Release | Jul 1, 2025 | |
| Reset | Jul 21, 2025 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Jul 1, 2025 | Jul 21, 2025 |
| ID | Term |
|---|---|
| D001943 | Breast Neoplasms |
| ID | Term |
|---|---|
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D001941 | Breast Diseases |
| D012871 | Skin Diseases |
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| 28802529 | Background | Shi RY, Yao QY, Wu LM, Xu JR. Breast Lesions: Diagnosis Using Diffusion Weighted Imaging at 1.5T and 3.0T-Systematic Review and Meta-analysis. Clin Breast Cancer. 2018 Jun;18(3):e305-e320. doi: 10.1016/j.clbc.2017.06.011. Epub 2017 Jul 5. |
| 30039037 | Background | Yilmaz E, Sari O, Yilmaz A, Ucar N, Aslan A, Inan I, Parlakkilic UT. Diffusion-Weighted Imaging for the Discrimination of Benign and Malignant Breast Masses; Utility of ADC and Relative ADC. J Belg Soc Radiol. 2018 Feb 7;102(1):24. doi: 10.5334/jbsr.1258. |
| D017437 |
| Skin and Connective Tissue Diseases |