Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
This is a Multicenter, Retrospective Real-world Study of Zanubrutinib in the Treatment of Chronic Lymphocytic Leukemia in China
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Zanubrutinib | Drug | patients with treatment naive or R/R CLL who treatment with Zanubrutinib |
| Measure | Description | Time Frame |
|---|---|---|
| Progression Free Survival (PFS) | PFS is defined as the duration from date of Zanubrutinib initiation to date of disease progression (PD [according to the physician's evaluation]) or death from any cause | up to two years |
| Measure | Description | Time Frame |
|---|---|---|
| Overall Survival | OS is defined as the time from the starting date of Zanubrutinib to the date of death due to any cause. | up to two years |
| Time to Next Therapy (TTNT) | The TTNT will be calculated as the difference between Zanubrutinib initiation date and initiation date of the first next therapy for CLL |
Not provided
Inclusion Criteria:
Exclusion Criteria:
-
Not provided
Not provided
Not provided
Investigators participating in this observational study should include all patients with CLL who initiated treatment with zanubrutinib over the period from July 1st, 2020 to the present, regardless of the treatment status at the time of inclusion. Thus, at the time of enrolment and retrospective data collection, patients may still be on treatment or have stopped treatment for any reason.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Shenmiao Yang | Contact | yangshenmiao@hotmail.com |
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Peking University People's Hospital | Beijing | Beijing Municipality | 100044 | China |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| C000629551 | zanubrutinib |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| up to two years |
| Adverse Events | Percentage of Participants with Adverse Events (AEs), Serious Adverse Events (SAEs) and Special Situations | up to two years |