The goal of this observational study is to investigate oral manifestations in patients with Chronic Kidney Disease (CKD) for early detection, that alterations play an important point for dental guide during the progression and type of treatment of CKD .

An oral exam was performed for detection oral manifestations, age, smoking, alcoholic and oral hygiene habits were collected.

The study has 3 groups under study: hemodialysis (HD), peritoneal dialysis (PD) and pre-dialysis (P-D)

Inclusion Criteria:

• Age ≥ 18 years and ≤ 80 years;
• No change of medication in the last 3 months;
• History of CKD comported by data laboratory (GRF<60 ml/min/1.73m²).

Exclusion Criteria:

• Age ≤ 18 years and ≥ 80 years;
• Patients undergoing orthodontic therapy;
• Patients taking drugs;
• Patients changes the medication or introduced a new medication.

Population with Chronic Kidney Disease, in pre-dialysis, hemodialysis, peritoneal dialysis