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Diabetic foot is a serious complication of diabetes mellitus that can lead to ulcerations, infections and, in extreme cases, amputations. Early detection of changes in skin temperature can help prevent these complications. Infrared thermography is a noninvasive technique that allows the visualization and quantification of skin temperature and could be an effective tool for the early detection of alterations in diabetic foot.
Objective
To evaluate the effectiveness of infrared thermography in the early detection and diagnosis of diabetic foot, comparing the temperatures of the feet of healthy subjects and subjects with diabetic foot.
Significant differences in foot temperatures are expected to be found between subjects with diabetic foot and healthy subjects. It is anticipated that areas of the foot at higher risk of ulceration in subjects with diabetic foot will show higher temperatures due to inflammation and changes in blood perfusion.
The results of the study could validate the use of thermography as an early detection and monitoring tool in patients at risk of developing diabetic foot. This could allow early and personalized interventions to prevent serious complications.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| healthy patients | Subjects healthy will rest barefoot for 15 minutes in a room at constant temperature (22-24°C). Thermographic images of both feet will be taken in multiple views (dorsal, plantar, lateral). Images will be analyzed to identify temperature differences between different areas of the foot and between study groups. |
| |
| diabetic foot patients | Subjects with diabetic foot, diagnosed with diabetes mellitus for more than 5 years, will rest barefoot for 15 minutes in a room at a constant temperature (22-24°C). Thermographic images of both feet will be taken in multiple views (dorsal, plantar, lateral). The images will be analyzed to identify temperature differences between different areas of the foot and between the study groups. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Termography | Diagnostic Test | Thermographic images of both feet will be taken in multiple views (dorsal, plantar, lateral). |
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| Measure | Description | Time Frame |
|---|---|---|
| Temperature maximun | Maximum foot temperatures | One measurement will be taken at the start of the study and another measurement the following year. |
| Temperature minimum | Minimum foot temperatures | One measurement will be taken at the start of the study and another measurement the following year. |
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Inclusion Criteria:
Subjects of both sexes. Age between 40 and 80 years. Diagnosis of type 1 or type 2 diabetes mellitus (for the case group). Absence of acute inflammatory diseases in the control group. Signed informed consent.
Exclusion Criteria:
Skin diseases that affect the interpretation of thermography. Recent treatment with medications that affect peripheral circulation. History of lower limb amputation.
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Healthy subjects or those with type 2 diabetes mellitus for more than 5 years who wish to participate in the study voluntarily, who will undergo a thermography of both feet.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| RAQUEL GARCIA DE LA PEÑA, DOCTOR | Contact | 954486530 | +34 | raquelgp@us.es |
| ANA M RAYO PEREZ, DOCTOR | Contact | 661604278 | +34 | anarayo43@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| RAQUEL GARCIA DE LA PEÑA, DOCTOR | University of Seville | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Seville | Seville | 41008 | Spain |
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| ID | Term |
|---|---|
| D017719 | Diabetic Foot |
| D003929 | Diabetic Neuropathies |
| D003925 | Diabetic Angiopathies |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D016523 | Foot Ulcer |
| D007871 | Leg Ulcer |
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Healthy subjects will have thermographic images of both feet taken in multiple views
| D012883 |
| Skin Ulcer |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D048909 | Diabetes Complications |
| D003920 | Diabetes Mellitus |
| D004700 | Endocrine System Diseases |
| D010523 | Peripheral Nervous System Diseases |
| D009468 | Neuromuscular Diseases |
| D009422 | Nervous System Diseases |