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Comparison of Oral Isotretinoin versus comparison of Oral Isotretinoin versus Antibiotics on Corneal Thickness in Patients with Acne Vulgaris
Acne is the most common skin disease requiring attention of health practitioners. It is a self-limiting disease of the pilosebaceous unit, which can lead to devastating and frustrating scars and pigmentary alterations.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Oral Isotretinoin | Other |
| |
| Antibiotics | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Oral Isotretinoin | Diagnostic Test | 20 mg/kg/day that affects sebaceous glands and is used to treat severe acne Frequency: Once daily |
|
| Measure | Description | Time Frame |
|---|---|---|
| Optical Coherence Tomography (OCT) | Standardized OCT imaging protocols to ensure consistency and accuracy across all measurements. | 12 Months |
| Snellen Chart | Visual acuity measured at 3-month and 6-month intervals. Units: Snellen fraction (e.g., 20/20, 20/40) | 12 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Shalamar Hospital Mughalpura | Lahore | Punjab Province | Pakistan |
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| ID | Term |
|---|---|
| D003316 | Corneal Diseases |
| ID | Term |
|---|---|
| D005128 | Eye Diseases |
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| ID | Term |
|---|---|
| D000900 | Anti-Bacterial Agents |
| ID | Term |
|---|---|
| D000890 | Anti-Infective Agents |
| D045506 | Therapeutic Uses |
| D020228 | Pharmacologic Actions |
| D020164 | Chemical Actions and Uses |
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| Antibiotics | Combination Product | 250 mg on laternate day/3 months Frequency: Once or twice daily |
|