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The study will compare a modified surgical approach for preserving fertility and minimizing hemorrhage in morbidly adherent placenta during cesarean section with a cervical tourniquet against uterine artery ligation.
Study Design and Setting This was prospective interventional study that comprised the medical data of 82 pregnant women with placenta accreta who had caesarean section. . This study will be carried out In the Department of Obstetrics and Gynecology, Minia Maternity University Hospital (MMUH) .
after being approved by the local ethical Committee; If placenta accreta was clinically verified preoperatively, all parturients were informed of the option of a hysterectomy. After receiving written, formal consent . After receiving documented formal consent. The study included all patients who had a scheduled cesarean procedure for placenta accreta. Obstetrical imaging either verified or strongly suspected the diagnosis. During the prenatal period, a senior sonographer evaluated all patients using ultrasonography and color Doppler technology. An ultrasonographic assessment was done. Each patient was evaluated for retroplacental sonolucent zones, vascular lacunas, myometrial thinning, bladder line disruption, and exophytic masses . The Color Doppler scan evaluated placental lacunar flow, hypervascularity in the vesicouterine interface, and continuous retroplacental venous complex structures. A 3D Doppler scan was used to assess hypervascularity of the uterine serosa and bladder interphase, as well as uneven intraplacental vascularization
Assessment :
To assess the effectiveness of the proposed management strategy, participants were separated into two groups. In Group 1 (n = 41), a cervical tourniquet was used systematically. In Group 2 (n=41), uterine artery ligation was performed prior to segmental resection for uterine preservation surgery
Surgical scenarios :
Across both groups: Ultrasonographic data determine whether an abdominal incision should be performed with a Pfannensteil or a vertical midline incision from under the umbilicus to above the pubic symphysis.
In another group : the same steps in group 1 in steps 1, 2 and 3 4- The bladder peritoneum is isolated from the uterus 5 - The uterine vessels were ligated in continuity at the level of the utero-vesical fold on each side.
6- the same steps in group 1 in steps 5,6, 7and 8
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group 1 (n = 41) cervical tourniquet | Experimental | in group 1 the investigators using a sterile Foley catheter (Ch 16/18 French) down to the lowest point and secures it "en bloc" around the cervix at the level of the uterosacral ligaments, approximately 3-4 cm below the incision. Then, tighten and fix . |
|
| Group 2 (n=41) uterine artery ligation | Experimental | in group 2the investigators ligated the uterine vessels in a continuous manner at the level of the utero-vesical fold on each side. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| cervical tourniquet | Procedure | After opening the abdominal wall, To reduce bleeding during PAS, make the uterine incision above the placenta's intrauterine borders . 2-investigators extract the uterus from the abdomen 3-An assistant slides a sterile Foley catheter (Ch 16/18 French) down to the lowest point and secures it "en bloc" around the cervix 4-The bladder peritoneum is isolated from the uterus 5-To remove myometrial tissue, leave a margin of at least 2 cm superior to the cervical internal ostium using electrocautery or scissors . |
| Measure | Description | Time Frame |
|---|---|---|
| operation time | recording total time of the surgery | intraoperative |
| repair time | recording length of defect repair from placental separation until uterine wall closure | intraoperative |
| Estimated blood loss | recording amount of blood loss | intraoperative |
| packed red blood cells transfusion | recording amount of red blood cell transfused | intraoperative until 24 hours after surgery |
| fresh frozen plasma (FFP) transfusion | recording amount of FFP transfusion | intraoperative until 24 hours postoperative |
| Number of Participants who had Bladder injuries | Number of Participants who had Bladder injuries | intraoperative until 2 weeks post operative |
| Number of Participants who had ureteral injuries | Number of Participants who had ureteral injuries | intraoperative until 2 weeks post operative |
| Number of Participants who had bowel injury | Number of Participants who had bowel injury |
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Inclusion Criteria:
Exclusion Criteria:
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| ID | Term |
|---|---|
| D010921 | Placenta Accreta |
| ID | Term |
|---|---|
| D007744 | Obstetric Labor Complications |
| D011248 | Pregnancy Complications |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
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| uterine artery ligation | Procedure | After opening the abdominal wall, To reduce bleeding during PAS, make the uterine incision above the placenta's intrauterine borders . 2-investigators extract the uterus from the abdomen 3-The bladder peritoneum is isolated from the uterus 4-The uterine vessels were ligated in continuity at the level of the utero-vesical fold on each side 5-To remove myometrial tissue, leave a margin of at least 2 cm superior to the cervical internal ostium using electrocautery or scissors . |
|
| intraoperative until 2 weeks post operative |
| surgical site infection | record the presence of wound infection | 24 hours until 1 month after surgery |
| urine output | recording amount of urine output | intraoperative |
| internal iliac artery ligation | recording if the internal iliac artery ligated whether it was unilateral or bilateral | intraoperative |
| pre-operative hemoglobin | recording amount of hemoglobin | preoperative |
| post-operative hemoglobin | recording amount of hemoglobin | postoperative within 6 hours from surgery |
| hospital stay | recording duration of hospital stay after surgery | postoperative until 10 days after surgery |
| ICU admission | recording the number of patients admitted to the ICU | immediate postoperative until 5 days after surgery |
| HDU high dependency unit admission | recording the number of patients admitted to high dependency unit | postoperative until 10 days after surgery |
| surgical diagnosis | strategy to preserving the uterus when managing placenta accreta versus hysterectomy | intraoperative |
| D010922 | Placenta Diseases |