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| Name | Class |
|---|---|
| Ministry of Science and ICT, Republic of Korea | OTHER_GOV |
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The investigators will prospectively collect clinical information to develop a clustering analysis model and confirm phenotype for patients with acute respiratory failure who admit to the intensive care unit and require oxygen supply beyond a high flow nasal cannula, and a control group without acute respiratory failure. and clinical characteristics and prognosis will be compared.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Acute Respiratory Failure group | Among patients admitted to the internal medicine intensive care unit at Samsung Seoul Hospital, if all of the following conditions are met:
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| Control group | For comparative analysis, among patients admitted to the internal medicine intensive care unit at Samsung Seoul Hospital who meet all of the following conditions, they are registered as a control group with the consent of the subjects and undergo the same research procedure.
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| Measure | Description | Time Frame |
|---|---|---|
| Hospital Mortality | clinical outcomes - Hospital Mortality | From date of admission until the date of hospital discharge or date of death from any cause, whichever came first, assessed up to 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| ICU Mortality | clinical outcomes - ICU Mortality | From date of ICU admission until the date of ICU discharge or date of death from any cause, whichever came first, assessed up to 6 months |
| Hospital length of stay |
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# Inclusion Criteria:
- Acute Respiratory Failure group
Among patients admitted to the internal medicine intensive care unit at Samsung Seoul Hospital, if all of the following conditions are met:
1) Age 18 or older 2) Patients who require treatment with high flow nasal cannula (HFNC), non-invasive ventilation (NIV (BIPAP or CPAP)), or mechanical ventilation (MV) due to acute respiratory failure.
- control group For comparative analysis, among patients admitted to the internal medicine intensive care unit at Samsung Seoul Hospital who meet all of the following conditions, they are registered as a control group with the consent of the subjects and undergo the same research procedure.
Age 18 or older
Patients who do not require high flow nasal cannula (HFNC), non-invasive ventilation (NIV (BIPAP or CPAP)), or mechanical ventilation (MV) treatment
If any of the following criteria applies, participants will not be permitted to participate in this clinical trial.
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ryoung Eun Ko, MD, PhD | Contact | +82-2-3410-6399 | koryoungeun@gmail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Samsung Medical Center | Recruiting | Seoul | Gangnam | 06351 | South Korea |
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Blood sample collection
: Within 24 hours after admission to the intensive care unit, and 2 to 5 days after admission to the intensive care unit, 18 ml of blood is collected in an ethylenediaminetetraacetic acid(EDTA) tube once (a total of 2 times, 36 ml) to analyze the following.
Broncho-Alveolar Lavage(BAL) fluid sample collection
Only for those subjects who undergo BAL during the treatment process, 5ml of BAL fluid will be collected and analyzed for the following.
clinical outcomes - Hospital length of stay
| From date of hospital admission until the date of hospital discharge, assessed up to 1 years |
| ICU length of stay | clinical outcomes - ICU length of stay | From date of ICU admission until the date of ICU discharge, assessed up to 6 months |