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| ID | Type | Description | Link |
|---|---|---|---|
| 2024-A00613-44 | Other Identifier | ANSM |
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Major progress achieved in diagnostic and therapeutic strategies has substantially improved the short-term prognosis of patients with pulmonary embolism (PE). These improvements have led to a shift from an acute to a chronic condition of venous thromboembolism, justifying the recent development of Chronic Thrombo-embolic Disease (CTED). In most of the situations, it is due to a residual pulmonary vascular obstruction (RPVO) which can be assessed by pulmonary scintigraphy.
Planar ventilation/perfusion (V/Q) scintigraphy is the gold standard, but for several months, V/Q single photon emission computed tomography (SPECT) is recommended in the guidelines.
The aim of this study is to evaluate the performances of various SPECT protocols to quantified RPVO and compared to planar scintigraphy to evaluate the RPVO.
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| Measure | Description | Time Frame |
|---|---|---|
| RPVO (%) | Evaluation of the RPVO establish with Meyer score (planar scintigraphy, 2D). The higher the percentage, the greater the obstruction of the lung | At inclusion |
| Segmental visual score | Evaluation of segmental visual score (SPECT-CT , 3D) The higher the percentage, the greater the obstruction of the lung | At inclusion |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with V/Q pulmonary SPECT-CT assess to rule out perfusion obstruction, patients admitted for a suspicion of PH, or a persistent dyspnea after PE
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Pierre-Benoit BONNEFOY, MD | Contact | (0)4 77 82 94 43 | +33 | pierre-benoit.bonnefoy@chu-st-etienne.fr |
| NATHALIE PREVOT, MD | Contact | (0)4 77 82 94 43 | +33 | nathalie.prevot@chu-st-etienne.fr |
| Name | Affiliation | Role |
|---|---|---|
| Pierre-Benoit BONNEFOY, MD | CENTRE HOSPITALIER DE SAINT-ETIENNE | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Centre Hospitalier Universitaire | Recruiting | Saint-Etienne | 42055 | France |
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