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Patients diagnosed with acute myeloid leukemia in the Second Hospital of Shanxi Medical University were selected and divided into the newly diagnosed group, the relapsed group, the complete remission group as the experimental group, and the healthy physical examination subjects as the control group. The relationship between IL-1β, catecholamine and norkephalin in peripheral blood of the experimental group and the control group was observed. According to the literature, the experimental group was significantly higher than the control group. In the experimental group, the newly diagnosed group was higher than the relapse group, and the relapse group was higher than the complete remission group, and the correlation was positive, and the difference was statistically significant.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| the newly diagnosed group |
| ||
| the relapsed group |
| ||
| the complete remission group |
| ||
| the control group |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Enzyme-linked immunosorbent assay | Diagnostic Test | Serum N/OFQ , IL-1β and NE levels were detected. |
|
| Measure | Description | Time Frame |
|---|---|---|
| N/OFQ | Serum N/OFQ levels | 24 hours |
| IL-1β | Serum IL-1β levels | 24 hours |
| NE | Serum NE levels | 24 hours |
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Inclusion Criteria:
In accordance with adult acute myeloid leukemia (non-acute promyelocytic leukemia)The diagnostic criteria for AML in the Chinese Diagnosis and Treatment Guidelines (2017 edition); ②Leukocyte count ≤ 25×109/L;
No treatment has been received in the past 6 months.
Exclusion Criteria:
Patients who are allergic to the drugs used in this study;
People with mental illness or cognitive impairment;
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Patients in the Second Hospital of Shanxi Medical University from June 2022 to November 2023
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Second Hospital of Shanxi Medical University | Taiyuan | Shanxi | 030001 | China |
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