Prognostic Recovery Observations and Guidance for Evaluating Stroke Survivors

Prognostic Recovery Observations and Guidance for Evaluating Stroke Survivors

This research delves into the acute prognostic factors influencing functional recovery in individuals who have experienced a stroke. The objective is to describe patterns of functional recovery after a stroke and identify new, clinically significant outcomes or metrics that can serve as predictive indicators for post-stroke functional recovery.

In this prospective observational study with additional procedures, the aim is to describe different patterns of recovery according to clinical characteristics identified during the early phases post stroke. All the additional procedure are functional and clinical tests or questionnaires validated and used for standard stroke clinical practice that pose no risk to the enrolled subject. This study, based at San Raffaele Hospital's stroke unit, will enrol subjects who suffer from stroke assessed in the acute phase (T0), at three-months (T1), six-month (T2) and 1-year post-stroke (T3). No intervention that can interfere with usual clinical practice will be administered between evaluations. Assessments include neurological, neuropsychological and physical therapy questionnaires along with functional tests validated and used in stroke clinical practice.

Inclusion Criteria:

• Age ≥ 18
• Haemorrhagic or ischaemic stroke confirmed by a clinical diagnosis and by brain imaging
• NIHSS item 5-6 ≥1
• 3 to 10 days post-stroke

Exclusion Criteria:

• Transient ischaemic attack
• Premorbid Modified Rankin Scale ≥ 4
• Acute orthopaedic complications
• Inability to give informed consent