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The goal of this clinical trial is to explore the effects of virtual reality use on maximal aerobic exercise test performance (aerobic capacity) in healthy adults. The main questions it aims to answer are:
Participants will complete a maximal aerobic exercise test two times (separated by 1 week of recovery) under the following conditions:
Researchers will compare the test results of both conditions to see if the use of a virtual reality program alters VO2peak or the ventilatory threshold.
Virtual reality imparts a dissociative effect on users during exercise, such that the physical activity task is experienced as more enjoyable and pleasant, requires less exertion, and requires less physiological function for a given submaximal work rate.
This array of positive effects may be particularly advantageous during a maximal aerobic exercise test, mainly because participant motivation and negative psychological state often lead to premature test termination. Ameliorating the unpleasantness of this type of exercise test with the use of virtual reality technology may prolong effort expenditure during the test and result in superior performance compared to a control condition.
Additionally, improving physiological function at submaximal work rates may lead to alterations in other important testing outcomes, particularly the ventilatory threshold. The ventilatory threshold is used as a reference point for prescribing exercise intensity. An intervention that modifies this value would have repercussions for physical fitness practitioners who prescribe exercise intensity relative to the ventilatory threshold.
The general purpose of this study is to determine the effect of virtual reality on maximal aerobic exercise test performance in healthy adults. The specific questions it aims to answer are:
Secondary questions this study aims to answer include:
Does using a virtual reality program during a maximal aerobic exercise test lead to differences in
To address these aims, participants will complete the same maximal aerobic exercise test on a cycler ergometer under normal laboratory conditions (Control) and when viewing an immersive virtual reality video (VR). The two tests will be completed in a randomized and counterbalanced order to account for learning or familiarity effects, and will be separated by 1 week to account for the effects of testing fatigue.
Respiratory data, HR, RPE, and affective valence were collected during the exercise tests to address the aims of the study.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control condition completed first | Experimental | In this arm, the Control condition (traditional maximal cardiorespiratory exercise test) will be completed first, and the Virtual Reality condition (traditional maximal cardiorespiratory exercise test with the addition of virtual reality video) will be completed second. |
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| Virtual Reality condition completed first | Experimental | In this arm, the Virtual Reality condition (traditional maximal cardiorespiratory exercise test with the addition of virtual reality video) will be completed first, and the Control condition (traditional maximal cardiorespiratory exercise test) will be completed second. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Virtual Reality condition | Behavioral | Participants will watch a video on a virtual reality headset during the completion of the maximal cardiorespiratory exercise test. |
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| Measure | Description | Time Frame |
|---|---|---|
| VO2peak | The highest level of oxygen uptake averaged over a 20-second period. | Assessed during the exercise test for each condition. |
| Ventilatory threshold | The work load (in Watts) during the maximal cardiorespiratory exercise test at which breakpoints are identified between metabolic measures associated with the ventilatory threshold (CO2 production and O2 utilization; ventilatory equivalent for O2 and O2 utilization; and excess CO2 production). | Assessed during the exercise test for each condition. |
| Measure | Description | Time Frame |
|---|---|---|
| Peak power | The work load (in Watts) of the highest exercise test stage that was completed | Assessed during the exercise test for each condition. |
| Total test time | The duration of the test (in minutes), not including the warm-up. |
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Inclusion Criteria:
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Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Andrew R Moore, PhD | Contact | 650-477-7746 | andmoore@augusta.edu |
| Name | Affiliation | Role |
|---|---|---|
| Andrew R Moore, PhD | Augusta University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Augusta University | Recruiting | Augusta | Georgia | 30909 | United States |
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot | Yes | No | No | Study Protocol | Feb 21, 2024 | Jun 7, 2024 | Prot_000.pdf |
| SAP | No | Yes | No | Statistical Analysis Plan | Jun 7, 2024 | Jun 13, 2024 | SAP_001.pdf |
| ICF | No | No | Yes | Informed Consent Form | Feb 21, 2024 | Jun 7, 2024 | ICF_002.pdf |
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This study will use a repeated-measures crossover model in which each participant completes the two conditions of the maximal exercise test (Control and Virtual Reality) in a randomized, counterbalanced order.
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It is not possible to mask the participant or data collection personnel from the conditions because the Virtual Reality condition requires that the headset be worn. Metabolic data and resulting outcomes (i.e. VO2peak value) will be analyzed by independent research assistants who will be blinded to the condition under which the data were gathered.
| Control condition | Behavioral | Participants will complete the maximal cardiorespiratory exercise test under control conditions without video, music, or other distractions. |
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| Assessed during the exercise test for each condition. |
| RPE | Rating of Perceived Exertion measured from 0 (no perceived exertion) to 10 (maximal perceived exertion). | Assessed throughout the exercise test for each condition (at the end of the warm-up and end of every even-numbered stage).. |
| Affective Valence | Affective valence measured from -5 (feeling very bad) to +5 (feeling very good). | Assessed throughout the exercise test for each condition (at the end of the warm-up and end of every even-numbered stage).. |
| %VO2peak at ventilatory threshold | The percentage of VO2peak at which the ventilatory threshold was reached. | Assessed during the exercise test for each condition. |
| Heart rate at ventilatory threshold | The heart rate corresponding to the time that the ventilatory threshold was reached. | Assessed during the exercise test for each condition. |
| Heart rate at VO2peak | The heart rate (in beats per minute) at which VO2peak was reached. | Assessed during the exercise test for each condition. |
| Respiratory Exchange Ratio (RER) at VO2peak | The proportion of carbon dioxide production to oxygen consumption when VO2peak was reached. | Assessed during the exercise test for each condition. |
| Respiratory Exchange Ratio (RER) at ventilatory threshold | The proportion of carbon dioxide production to oxygen consumption when the ventilatory threshold was reached. | Assessed during the exercise test for each condition. |