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Compared with the patients with episodic migraine those with chronic migraine have worst quality of life and more severe headache related disability we investigate Repetitive transcranial magnetic stimulation in treatment and prophylaxis of chronic migraine
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| group (1) will rTMS over left motor cortex | Active Comparator | Repetitive transcranial magnetic stimulation parameters: stimulation site: left motor cortex intensity: 70% of resting motor threshold frequency: 15 Hz number of pulses: 30 number of trains: 40 |
|
| group (2) will receive rTMS over left dorsolateral prefrontal cortex | Active Comparator | Repetitive transcranial magnetic stimulation parameters: stimulation site: left dorsolateral prefrontal cortex intensity: 70% of resting motor threshold frequency: 15 Hz number of pulses: 30 number of trains: 40 |
|
| group (3) will receive rTMS over left dorsolateral prefrontal cortex and left motor cortex | Active Comparator | Repetitive transcranial magnetic stimulation parameters: stimulation site: left dorsolateral prefrontal cortex and left motor cortex intensity: 70% of resting motor threshold frequency: 15 Hz number of pulses: 30 number of trains: 40 |
|
| group (4) will receive sham stimulation | Sham Comparator | Repetitive transcranial magnetic stimulation parameters: stimulation site: the coil will be perpendicular over vertex of skull intensity: 70% of resting motor threshold frequency: 15 Hz number of pulses: 30 number of trains: 40 |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| transcranial magnetic stimulation device | Device | Repetitive transcranial magnetic stimulation parameters: stimulation site: left dorsolateral prefrontal cortex and left motor cortex intensity: 70% of resting motor threshold frequency: 15 Hz number of pulses: 30 |
| Measure | Description | Time Frame |
|---|---|---|
| improvement of headache severity and number of attacks of headache before and after intervention by visual analogue scale and headache impact test | improvement of headache severity and number of attacks of headache before and after intervention by visual analogue scale and headache impact test | one month after treatment |
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Inclusion criteria:
Exclusion criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Tarek Mohamed | Contact | 01025545002 | tarikmohamed@med.sohag.edu.eg |
| Name | Affiliation | Role |
|---|---|---|
| Tarek Mohamed | Sohag faculty of medicine | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sohag faculty of medicine | Recruiting | Sohag | 02 | Egypt |
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the patient will divide into 4 groups first group will receive stimulation over the left motor cortex second group will receive stimulation over left dorsolateral prefrontal cortex third group will receive stimulation over both left motor cortex and left dorsolateral prefrontal cortex fourth group will receive sham stimulation
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