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Evaluation of maxillary alveolar ridge changes (bone quantity and quality as revealed by Radiographic and Histomorphometry) utilizing microfragmented adipose tissue loaded on bovine graft versus bovine graft only for maxillary posterior ridge preservation.
All patients involved in this study will be divided into two groups; each group will receive a different graft of bone augmentation: Adipose tissue loaded on bovine graft will be utilized for the study group and bovine raft only for the control group.
After 6 months, patients will be evaluated histomorphometrically via core biopsy at the time of implant placement and radiographically via assessment of ridge height on CBCT.
Radiographic assessment that will be achieved by CBCT scan will be used to calculate the changes of bone height from base line (1week) to 6 months postoperatively.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| microfragmented adipose tissue | Experimental | microfragmented adipose tissue loaded on bovine graft on ridge preservation |
|
| bovine graft | Active Comparator | bovine graft only on ridge preservation |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| microfragmented adipose tissue loaded on bovine graft | Procedure | microfragmented adipose tissue loaded on bovine graft on ridge preservation |
|
| Measure | Description | Time Frame |
|---|---|---|
| Quantity of bone (vertical bone height) | By CBCT | Quantity of bone (vertical bone height) by CBCT after 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Quality of bone | Histological analysis (Core biopsy) Percentage of newly formed bone | Histological analysis (Core biopsy) Percentage of newly formed bone after 6 months |
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Inclusion Criteria:
Patients requiring implant treatment after tooth extraction due to either unrestorable caries lesions or affected periodontium.
Exclusion Criteria:
General contraindications to implant surgery.
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Bshaer Bayashot, BDS | Contact | 01064825199 | bshaer.bayashot@dentistry.cu.edu.eg | |
| Hesham Elhawary, prof | Contact | 01144446373 | hesham.elhawary@dentistry.cu.edu.eg |
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All patients involved in this study will be divided into two groups; each group will receive a different graft of bone augmentation: Adipose tissue loaded on bovine graft will be utilized for the study group and bovine raft only for the control group.
For both groups: All Patients of both groups will be evaluated radiographically immediately and after 6 months post-operative by cone beam CT scan to record Alveolar ridge height.
After 6 months, patients will be evaluated histomorphometrically via core biopsy at the time of implant placement and radiographically via assessment of ridge height on CBCT.
Radiographic assessment that will be achieved by CBCT scan will be used to calculate the changes of bone height from base line (1week) to 6 months postoperatively.
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| ID | Term |
|---|---|
| D014086 | Tooth Mobility |
| ID | Term |
|---|---|
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
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