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The goal of this randomized clinical trial is to learn the effect of using local corticosteroids and maintaining apical patency in reducing post-preparation pain in patients with acute irreversible pulpitis in molar teeth. The main question it aims to answer is:
• How effective are using local corticosteroids and maintaining apical patency in reducing post-preparation pain in patients with acute irreversible pulpitis? Participants will be asked to fill a visual analogue scale to record their pain, after receiving a root canal treatment while using local corticosteroids or not as well as maintaining apical patency or not.
Researchers will compare the use of corticosteroids and maintaining apical patency in reducing post-operative pain.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| No apical patency | Sham Comparator |
| |
| Apical patency | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Non-corticosteroid injection | Procedure | no infiltration injection of 0.7 ml of dexamethasone lateral to the involved tooth after anesthesia administration. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Post-operative pain | Patients were instructed to record their pain level using the Visual Analog Scale | 6, 12, 24, 48, 72 hour and 7 days postoperative intervals |
| Inflammatory markers | Gingival crevicular fluid samples were collected by periopaper for testing the level of IL-1β and IL-10 | before treatment, after 3 days and after 7 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Mustafa Sultan | Contact | +201111506890 | sultan_mustafa@hotmail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Suez Canal University | Recruiting | Ismailia | Egypt |
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| Corticosteroid injection | Drug | infiltration injection of 0.7 ml of dexamethasone lateral to the involved tooth after anesthesia administration. |
|
| ID | Term |
|---|---|
| D010149 | Pain, Postoperative |
| D011671 | Pulpitis |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D003788 | Dental Pulp Diseases |
| D014076 | Tooth Diseases |
| D009057 | Stomatognathic Diseases |
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| ID | Term |
|---|---|
| D000305 | Adrenal Cortex Hormones |
| ID | Term |
|---|---|
| D006728 | Hormones |
| D006730 | Hormones, Hormone Substitutes, and Hormone Antagonists |
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