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| Name | Class |
|---|---|
| Emory University | OTHER |
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Early identification of intracranial atherosclerotic disease (ICAD) may impact the management of patients undergoing mechanical thrombectomy (MT). The aim of the study is to develop and validate a scoring system for pre-thrombectomy diagnosis of ICAD in posterior circulation large vessel/distal medium vessel occlusion strokes (LVOs/DMVOs).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| ICAD group | includes ICAD-related stroke made when a smooth-bordered lesions leading to delayed perfusion on conventional-angiography (without competing stroke etiology) or when irregular-surfaced lesions involving the target vessel during mechanical thrombectomy were unveiled (with or without competing stroke etiology). |
| |
| Non-ICAD cases (controls) | Non-ICAD cases (controls) includes patients with posterior circulation stroke attributed to stroke etiologies other than ICAD. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| we are aiming to develop a Scoring system based on certain variables derived from both groups | Other | We are aiming to develop a Scoring system based on certain variables derived from both group |
| Measure | Description | Time Frame |
|---|---|---|
| Post-procedural outcomes included any intracranial hemorrhage, symptomatic ICH (sICH) | sICH is defined as local or remote parenchymal hemorrhage type 2, subarachnoid hemorrhage, and/or intraventricular hemorrhage, combined with a neurological deterioration of 4 points or more on the NIHSS from baseline or leading to death that the physician judged was causative of the deterioration) per ECASS III criteria | June 1st, 2025 |
| Measure | Description | Time Frame |
|---|---|---|
| 90 day modified Rankin scale (mRS) | a score of 0 to 4 on the modified Rankin scale (range, 0 to 6, with a score of 0 indicating no disability, 4 moderately severe disability, and 6 death) at 90 days, was changed to a good functional status (a modified Rankin scale score of 0 to 3, with a score of 3 indicating moderate disability) | June 1st, 2025 |
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Inclusion Criteria:
Exclusion Criteria:
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The cohort is divided into 2 groups;
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Marcus stroke and neuroscience center, Grady Memorial Hospital | Atlanta | Georgia | 30303 | United States |
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| 90 day mortality | June 1st, 2025 |
| Sohag university hospitals | Sohag | 82524 | Egypt |
|
| ID | Term |
|---|---|
| D000083242 | Ischemic Stroke |
| D002537 | Intracranial Arteriosclerosis |
| D020520 | Brain Infarction |
| ID | Term |
|---|---|
| D020521 | Stroke |
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D020765 | Intracranial Arterial Diseases |
| D001161 | Arteriosclerosis |
| D001157 | Arterial Occlusive Diseases |
| D002545 | Brain Ischemia |
| D007238 | Infarction |
| D007511 | Ischemia |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D009336 | Necrosis |
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