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Hemorrhagic Myocardial infarctions are at high risk for mechanical complications including cardiac rupture. Prediction of vulnerable myocardial segments is an important step for the stratification of hemorrhagic MI patients. Wall motion index ratio is an important parameter to determine regions of high vulnerability within the 17-segment LV model of hemorrhagic MI.
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| Measure | Description | Time Frame |
|---|---|---|
| Wall Strain Index for Potential Detection of Intramyocardial Hemorrhage | Difference in Wall Strain Index values between patients with intramyocardial hemorrhage and those without, confirmed by cardiac MRI. | 48 hours Post-PCI |
| Wall Strain Index in Detecting the Severity of Intramyocardial Hemorrhage | Relationship between initial Wall Strain Index measurements and the volume of intramyocardial hemorrhage quantified by cardiac MRI | 48 hours Post-PCI |
| Wall Strain Index Ratio in Identification of Vulnerable LV Segments for Cardiac Rupture | Wall Strain Index Ratio for circumferential and longitudinal strain in identifying vulnerable hemorrhagic left ventricular segments at risk for rupture | 48 hours Post-PCI |
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Inclusion Criteria:
Exclusion Criteria:
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The study population consists of individuals aged 18 to 80 who have been diagnosed with acute ST-elevation myocardial infarction (STEMI) and are scheduled for emergency percutaneous coronary intervention (PCI).
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| Name | Affiliation | Role |
|---|---|---|
| Rohan Dharmakumar, PhD | Indiana University | Study Director |
| Keyur P Vora, MD FACC | Indiana University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Krannert Cardiovascular Research Center, Indiana University School of Medicine | Indianapolis | Indiana | 46202 | United States |
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| ID | Term |
|---|---|
| D017682 | Myocardial Stunning |
| D015428 | Myocardial Reperfusion Injury |
| D006342 | Heart Rupture, Post-Infarction |
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D009202 | Cardiomyopathies |
| D017202 | Myocardial Ischemia |
| D014652 | Vascular Diseases |
| D015427 | Reperfusion Injury |
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D006341 | Heart Rupture |
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