Changes in Eye Shape With Myopia Management Interventions

Longitudinal Changes in Eye Shape in Young Adults Treated With Low-Dose Atropine and Soft Multifocal Contact Lenses

The goal of this clinical trial is to study changes in eye shape of nearsighted young adults using low-dose atropine eye drops or soft multifocal contact lenses. The main questions it aims to answer are:

• do low-dose atropine and soft multifocal contact lenses affect the shape of the peripheral eye?
• are changes in peripheral eye shape from these interventions influenced by changes in the focusing system of the eye?

Participants will:

• have multiple different types of photos taken
• have their prescription for glasses/contacts checked
• have their eye health checked, including the use of dilating eye drops
• be randomly assigned to use eye drops every night or wear special contact lenses daily instead of their typical contacts
• will complete five study visits over the course of 12 months

Researchers will compare young adults using low-dose atropine to those wearing soft multifocal contact lenses and to those using no intervention to see if using these interventions affects retinal shape.

Inclusion Criteria:

• best corrected visual acuity of 20/25 or better in each eye
• nearsighted
• current contact lens wearer
• normal binocular vision (to be determined by an examiner at the first study visit)

Exclusion Criteria:

• eye diseases (including lazy eye or eye turn)
• pregnant, nursing, or planning a pregnancy in the next 12 months
• history of refractive surgery (e.g., LASIK)
• history of myopia control treatment
• sensitivity to anesthetics or preservative in eye drops
• difficulty with pupillary dilation