Clinico-biological Collection of Bone, Calcium and Growth... | NCT06444503

Studies
Clinico-biological Collection of Bone, Calcium and Growth Plate Pathologies

NCT06444503

Sponsor

University Hospital, Toulouse

Status

Recruiting

Last Update Posted

Jun 5, 2026Actual

Enrollment

350Estimated

Phase

Not provided

Conditions

Bone Disorder

Interventions

Biological samples
Biological

Countries

France

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Jun 2026

Overall Recruitment Status or Expanded Access Status

Recruiting

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Sep 16, 2024Actual

Primary Completion Date

Sep 16, 2034Estimated

Completion Date

Sep 16, 2034Estimated

First Submitted Date

May 30, 2024

First Submission Date that Met QC Criteria

May 30, 2024

First Posted Date

Jun 5, 2024Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Jun 3, 2026

Last Update Posted Date

Jun 5, 2026Actual

Oversight Module

Has Data Monitoring Committee (DMC)

Is FDA Regulated Drug

Is FDA Regulated Device

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

Not provided

FDAAA801 Violation

Not provided

Description Module

Brief Summary

The aim of this project is to set up a biological and clinical collection of patients with progressive bone, calcium and growth plate pathologies.

This collection will provide a better understanding of the mechanisms involved in growth plate and bone damage in these diseases and identify factors predictive of progression and new therapeutic targets.

Detailed Description

Not provided

Design Module

Study Type

Observational

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Target Follow-Up Duration

Not provided

Phases

Not provided

Interventional Study Design

Allocation

Not provided

Intervention Model

Biospecimen

Retention

Enrollment

350Estimated

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Patients suffering from growth plate or bone pathology		As part of their pathology, patients benefit from clinical monitoring and regular blood and urine tests.	Other: Biological samples Other: Biological

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Biological samples	Other	Blood and urine will be taken in larger quantity	Patients suffering from growth plate or bone pathology

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Building a collection of biological samples and clinical-biological data from patients presenting bone, calcium and growth plate pathologies	Blood and urine sampling	Day 0 and through study completion, an average of 5 years

Secondary Outcomes

Measure	Description	Time Frame
Identification of potential markers of disease progression based on new knowledge.		Day 0 and through study completion, an average of 5 years

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

Children (from birth) with growth plate or bone pathology
Patients affiliated to or benefiting from a social security scheme
Patients able to receive information about the study and to understand the information form in order to participate in the study. This implies :
mastery of the French language
Not being subject to a restriction of rights by the judicial authorities
Patients or legal representatives having given their consent to participate in the study (expression of non-opposition).

Exclusion Criteria:

Patients under legal protection (guardianship, curatorship or safeguard of justice)
Pregnant or breast-feeding women

Accepts Healthy Volunteers

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

Not provided

Maximum Age

99 Years

Standard Ages

ChildAdultOlder Adult

Study Population

Patients with with growth plate or bone pathology.

Sampling Method

Non-Probability Sample

Contacts/Locations Module

Central Contacts

Name	Role	Phone	Extension	Email
Thomas EDOUARD, MD	Contact	0534558555	+33	edouard.t@chu-toulouse.fr
Sanaa EDDIRY	Contact	0561776110	+33	eddiry.s@chu-toulouse.fr

Overall Officials

Name	Affiliation	Role
Thomas EDOUARD, MD	University Hospital, Toulouse	Principal Investigator

Locations

Facility	Status	City	State	ZIP	Country	Contacts
University Toulouse Hospital	Recruiting	Toulouse		31000	France

IPD Sharing Statement Module

Plan to Share IPD

Description

Not provided

Types

Not provided

Time Frame

Not provided

Access Criteria

Not provided

URL

Not provided