The goal of this observational study is to evaluate the joint prognostic effects of physical function and mental health on survival of cancer survivors.

Cancer survivors were selected from the National Health and Nutrition Examination Survey (NHANES) between 2007 and 2018. Total sedentary time was assessed by self-reported daily hours of sitting and depressive symptoms were assessed by Patient Health Questionnaire 9 (PHQ-9). Kaplan-Meier (KM) curves and the Cox regression analyses were used to evaluate the separate and joint prognostic effects of sedentary behavior and depressive symptoms with mortality outcomes of cancer survivors.

Inclusion Criteria:

• Adults with aged above 18 year old

Exclusion Criteria:

• Without a history of cancers
• Without records of sedentary behavior or depressive symptoms test
• Incomplete follow-up information

Cancer survivors were selected from the National Health and Nutrition Examination Survey (NHANES) program between 2007 and 2018.