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We have developed a novel inadequate bowel preparation prediction model based on a systematic review and meta-analysis. The goal of this multicenter observational study is to validate the accuracy of this model.
The primary outcome is quality of bowel preparation. The secondary outcomes include polyp/adenoma detection rate, willingness of undergoing colonoscopy again and adverse events.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients undergoing colonoscopy in General Hospital of Northern Theater Command | Patients were informed to eat semi-liquid and non-slag diet for breakfast and lunch and full-liquid diet for dinner on the day before colonoscopy, and be fasting on the day of colonoscopy. A split-dose 3 L PEG regimen was used for all patients. |
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| Patients undergoing colonoscopy in First Affiliated Hospital of China Medical University | Patients were informed to eat semi-liquid and non-slag diet for breakfast and lunch and full-liquid diet for dinner on the day before colonoscopy, and be fasting on the day of colonoscopy. A split-dose 2 L PEG regimen was used for all patients. |
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| Inpatients undergoing colonoscopy in Second Affiliated Hospital of Army Medical University | We retrospectively collect data of inpatients undergoing colonoscopy. Patients were informed to eat semi-liquid and non-slag diet for breakfast and lunch and full-liquid diet for dinner on the day before colonoscopy, and be fasting on the day of colonoscopy. A full-dose 3 L PEG regimen was used for all patients. |
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| Patients undergoing colonoscopy in No. 960 Hospital | Patients were informed to eat semi-liquid and non-slag diet for breakfast and lunch and full-liquid diet for dinner on the day before colonoscopy, and be fasting on the day of colonoscopy. Split-dose 3 L PEG, sodium phosphate or sodium picosulfate regimen were used according to the doctor's advice. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Bowel preparation before colonoscopy | Procedure | Patients use purgative for bowel cleansing before colonoscopy. |
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| Measure | Description | Time Frame |
|---|---|---|
| Quality of bowel preparation | A total BBPS score ≥6 with BBPS score ≥2 for each colon segment was considered to have adequate bowel preparation. Each segment of the colon is scored from 0 to 3, with higher scores indicating superior cleansing, and summed for a total score that can range from 0 to 9. | During the procedure of colonoscopy |
| Measure | Description | Time Frame |
|---|---|---|
| Adenoma and/or polyp detection rate | Proportion of patients with at least one adenoma and/or polyp detected during colonoscopy | During the procedure of colonoscopy |
| Number of polyps and/or adenomas |
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Inclusion Criteria:
Exclusion Criteria:
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Adult patients undergoing colonoscopy
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| Name | Affiliation | Role |
|---|---|---|
| Xingshun Qi | Department of Gastroenterology, General Hospital of Northern Theater Command | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Gastroenterology, General Hospital of Northern Theater Command (formerly called General Hospital of Shenyang Military Area) | Shenyang | Liaoning | 110840 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 19136102 | Background | Lai EJ, Calderwood AH, Doros G, Fix OK, Jacobson BC. The Boston bowel preparation scale: a valid and reliable instrument for colonoscopy-oriented research. Gastrointest Endosc. 2009 Mar;69(3 Pt 2):620-5. doi: 10.1016/j.gie.2008.05.057. Epub 2009 Jan 10. | |
| 41578308 | Derived | Wang W, Tong L, Li S, He W, Huang J, Liu X, Wang C, Xia J, Qi X, Song C. Development and multicenter external validation of a novel prediction model for inadequate bowel preparation before colonoscopy. BMC Med Inform Decis Mak. 2026 Jan 23;26(1):46. doi: 10.1186/s12911-026-03348-w. |
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Number of polyps and/or adenomas detected during colonoscopy
| During the procedure of colonoscopy |
| Adverse events | Incidence of abdominal pain, bloating, nausea/vomiting after intake of purgative. | Before the procedure of colonoscopy |