Monitoring Nociception Using NoL Index to Reduce Opioid-Related Complications in Laparoscopic Abdominal Surgery

Monitoring Nociception Using NoL Index and Its Implications in Reducing Opioid-Related Complications in Laparoscopic Abdominal Surgery

This study aims to determine if optimal intraoperative nociception monitoring using the NoL index can reduce postoperative complications related to opioid use in laparoscopic abdominal surgery. The hypothesis is that guided nociception monitoring decreases opioid-related complications and improves postoperative outcomes.

The study is a prospective, observational cohort study conducted across multiple centers. It aims to evaluate the impact of intraoperative nociception monitoring on postoperative opioid-related complications. The study will involve two groups of patients undergoing laparoscopic abdominal surgery: one group with visible NoL monitoring and another with non-visible NoL monitoring.

Inclusion Criteria:

• Age ≥ 18 years
• Scheduled for laparoscopic abdominal surgery
• Undergoing balanced general anesthesia
• ASA physical status I-III
• Signed informed consent

Exclusion Criteria:

• Refusal to participate
• Communication barriers
• Multimodal, opioid-free, or regional epidural anesthesia
• ASA IV or V
• Pregnant or breastfeeding women
• Open or emergency abdominal surgery
• Post-surgery transfer to ICU or Recovery Unit