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Collect standardized, structured, and comprehensive disease-specific information, produce high-quality and accurate clinical data, provide a sample basis for the analysis and mining of spinal cord injury clinical big data, and establish a spinal cord injury-specific disease data platform to serve clinical work. Promote multi-center cooperation in spinal cord injury research: Establish a unified, standardized, queryable, and sharable efficient spinal cord clinical research data platform to promote multi-center cooperation in spinal cord injury clinical research and enhance the international competitiveness of this research field. Help the region to prepare for the establishment of a spinal cord injury-specific disease data platform for various hospitals in the region, forming a spinal cord injury-specific disease network center to achieve data sharing.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control, SCI-1, SCI-2, SCI-3 | Control: No spinal cord injury |
| |
| SCI-1 | SCI-1: spinal cord injury and ASIA Grade A and B |
| |
| SCI-2 | SCI-2: spinal cord injury and ASIA Grade C |
| |
| SCI-3 | SCI-3: spinal cord injury and ASIA Grade D |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| MRI | Radiation | Every patient needs an MRI to assess spinal cord injury. This is one of the clinically necessary examinations. |
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| Measure | Description | Time Frame |
|---|---|---|
| MRI image | original MRI image format DICOM to Nii was based on Python (Version: 3.10.6), and those would be loaded into the MRIcroGMRI imageL software (Version: 12.2). Three spinal surgeons (with 5, 8 and 18 years of experience in interpreting spinal MRI respectively) manually depict the region of interest (ROI) of the lesion area layer by layer, to form three dimensional (3D) volume of interest (VOI). After the primary spinal surgeon finished depicting the injured spinal cord, the senior spinal surgeon checked the quality of ROI and made some adjustments. | From 2016 to 2027 |
| ASIA scores | ASIA scores means American Spinal Injury Association Impairment Scale. ASIA has 5 grades depends on the severity of spinal cord injury. Grade A :No sensory or motor function is preserved in sacral segments S4-S5, no sacral sparing. Grade B:Sensory but not motor function is preserved below the neurological level and includes sacral segments S4-S5, AND No motor function is preserved more than three levels below the motor level on either side of the body. Grade C: Motor function is preserved below the neurological level AND More than half of the key muscle functions below the neurological level of injury have a muscle grade of less than 3 (Grades 0-2). Grade D: Motor function is preserved below the neurological level AND At least half (half or more) of the key muscle functions below the neurological level of injury have a muscle grade ≥ 3. Grade E: If sensation and motor function are graded as normal in all segments AND the patient had prior SCI-related deficits. | From 2016 to 2027 |
| Measure | Description | Time Frame |
|---|---|---|
| Age | Years old, no need month nor day | From 2016 to 2027 |
| Gender | male and female | From 2016 to 2027 |
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Inclusion Criteria:
Exclusion Criteria:
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MRI image of patients within 48 hours after TCSCI in The First People's Hospital of Nantong
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Affiliated 2 Hospital of Nantong University | Recruiting | Nantong | Jiangsu | 0513 | China |
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| ID | Term |
|---|---|
| D013119 | Spinal Cord Injuries |
| ID | Term |
|---|---|
| D013118 | Spinal Cord Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D020196 | Trauma, Nervous System |
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| Weight | In kilograms | From 2016 to 2027 |
| Height | In meters | From 2016 to 2027 |
| BMI | In kg/m^2 | From 2016 to 2027 |
| D014947 | Wounds and Injuries |