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| Name | Class |
|---|---|
| Institute for Clinical and Experimental Medicine | OTHER_GOV |
| Brno University Hospital | OTHER |
| České Budějovice Hospital | OTHER |
| University Hospital Hradec Kralove |
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The project is a national, prospective, multicenter, non-interventional pilot project of screening HCV in PWID in the Czech Republic.
The main goal of the project is to methodically prepare, implement and evaluate a pilot project that will verify the suitability of the proposed procedure of early detection of Hepatitis C and setting up and testing new methods and implementation into the system of social health care.
The project is a national, prospective, multicenter, non-interventional pilot project of screening HCV in PWID in 18 clinical centers in the Czech Republic.
The main goal of the project is the elimination of further transmission of hepatitis C virus and to methodically prepare, implement and evaluate a pilot project that will verify the suitability of the proposed procedure of early detection of Hepatitis C and setting up and testing new methods and implementation into the system of social health care.
The project will include testing the procedure on a sample of approx. 3,000 PWID which can help to identify weak points in the continuum of care. A methodology for the continuous care of the target group in the early diagnostic and therapeutic stages will be created. Proposal for a system change towards streamlining the screening process.
The project is supported by the European Social Fund (Operational Program Employment plus) and the state budget of the Czech Republic and is registered by the Ministry of Labour and Social Affairs of the Czech Republic under ID: CZ.03.02.02/00/22_005/0000281.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| People who inject drugs |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Hepatitis C antibody (anti-HCV) test | Diagnostic Test | Testing for hepatitis C antibodies determines whether or not you have been exposed to HCV at some point in your life. This testing will be performed in all 3,000 persons who inject drugs enrolled in the project. |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of the hepatitis C virus in screened cohort of persons who inject drugs | Until 31. 12. 2025 |
| Measure | Description | Time Frame |
|---|---|---|
| Up to 3,000 persons who inject drugs (PWID) enrolled in the project | Until 31. 12. 2025 | |
| Optimal methodological settings for early detection of the Hepatitis C virus based on hepatitis C antibody and hepatitis C RNA testing | Until 31. 12. 2025 |
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Inclusion Criteria:
Exclusion Criteria:
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Any people who inject drugs with age 18+ tested by cetres participating in the project.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Nikola Stourac | Contact | +42073901254 | nikola.stourac@uzis.cz | |
| Lucie Mandelova, PhD | Contact | +420 770190 828 | lucie.mandelova@uzis.cz |
| Name | Affiliation | Role |
|---|---|---|
| Viktor Mravcik, assoc. prof. | Charles University First Faculty of Medicine | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Brno University Hospital | Recruiting | Brno | Czechia |
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| OTHER |
| University Hospital Olomouc | OTHER |
| Hepatogastroenterology Hradec Kralove | UNKNOWN |
| Regional Hospital Karlovy Vary | UNKNOWN |
| Clinic Podane ruce | UNKNOWN |
| Tomáš Baťa Regional Hospital in Zlín | UNKNOWN |
| Hospital Agel Prostějov | UNKNOWN |
| Hospital Jihlava | UNKNOWN |
| Hospital Havířov | UNKNOWN |
| Hospital Tábor | UNKNOWN |
| Remedis Prague | UNKNOWN |
| Hospital Opava | UNKNOWN |
| Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s. | OTHER |
| Military University Hospital, Prague | OTHER |
| Hospital Pardubice | UNKNOWN |
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| Hepatitis C RNA test and genotype test | Diagnostic Test | RNA is a type of genetic material from HCV that can be detected in the blood. This test will be used as a confirmation of the infection. This testing will be performed in all persons with positive antibody test who will come to clinical center. |
|
| Clinic Podane ruce | Recruiting | Brno | Czechia |
|
| České Budějovice Hospital | Recruiting | České Budějovice | Czechia |
|
| Hospital Havířov | Recruiting | Havířov | Czechia |
|
| Hepatogastroenterology Hradec Kralove | Recruiting | Hradec Králové | Czechia |
|
| University Hospital Hradec Kralove | Recruiting | Hradec Králové | Czechia |
|
| Hospital Jihlava | Recruiting | Jihlava | Czechia |
|
| Regional Hospital Karlovy Vary | Recruiting | Karlovy Vary | Czechia |
|
| University Hospital Olomouc | Recruiting | Olomouc | Czechia |
|
| Hospital Opava | Recruiting | Opava | Czechia |
|
| Hospital Pardubice | Recruiting | Pardubice | Czechia |
|
| Institute for Clinical and Experimental Medicine | Recruiting | Prague | Czechia |
|
| Military University Hospital, Prague | Recruiting | Prague | Czechia |
|
| Remedis Prague | Recruiting | Prague | Czechia |
|
| Hospital Agel Prostějov | Recruiting | Prostějov | Czechia |
|
| Hospital Tábor | Recruiting | Tábor | Czechia |
|
| Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s. | Recruiting | Ústí nad Labem | Czechia |
|
| Tomáš Baťa Regional Hospital in Zlín | Recruiting | Zlín | Czechia |
|
| ID | Term |
|---|---|
| D006526 | Hepatitis C |
| D006505 | Hepatitis |
| ID | Term |
|---|---|
| D000086982 | Blood-Borne Infections |
| D003141 | Communicable Diseases |
| D007239 | Infections |
| D006525 | Hepatitis, Viral, Human |
| D014777 | Virus Diseases |
| D018178 | Flaviviridae Infections |
| D012327 | RNA Virus Infections |
| D008107 | Liver Diseases |
| D004066 | Digestive System Diseases |
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