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- For treating unwanted tattoos, the gold standard treatment is a nanosecond or picosecond laser. However, comparative microscopic analysis is limited. Therefore, the aim of the present study is to analysis morphological changes of tattoo particles and surrounding tissue in human skin.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Nanosecond laser | Patients with unwanted tattoos who plan a nanosecond laser treatment will be recruited for measurements using a multiphoton-tomography system. |
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| Picosecond laser | Patients with unwanted tattoos who plan a picosecond laser treatment will be recruited for measurements using a multiphoton-tomography system. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| picosecond laser treatment + measurement with a multiphoton tomography system | Other | Patients with unwanted tattoos who plan a laser treatment will be recruited for measurements using a multiphoton-tomography system. These are scheduled 6 weeks and 12 weeks post-treatment. |
| Measure | Description | Time Frame |
|---|---|---|
| Size of intercellular spaces | Size of intercellular spaces after picosecond or nanosecond laser treatment. | 6 weeks and 12 weeks post-treatment |
| Size of keratinocytes | Size of keratinocytes after picosecond or nanosecond laser treatment. | 6 weeks and 12 weeks post-treatment |
| Size of tattoo particles | Size of tattoo particles after picosecond or nanosecond laser treatment. | 6 weeks and 12 weeks post-treatment |
| Distribution of tattoo particles | Distribution though the epidermal and dermal layers after picosecond or nanosecond laser treatment. | 6 weeks and 12 weeks post-treatment |
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Inclusion Criteria:
- healthy patients who plan a laser treatment of their unwanted tattoo/ tattoos at our department
Exclusion Criteria:
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- healthy patients who plan a laser treatment of their unwanted tattoo/ tattoos at our department
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Lynhda Nguyen, Dr. med. | Contact | +49 (0) 7410-0 | l.ngyuen@uke.de |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Medical Center Hamburg-Eppendorf | Recruiting | Hamburg | 20251 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 35837813 | Background | Nguyen L, Mess C, Schneider SW, Huck V, Herberger K. In vivo visualisation of tattoo particles using multiphoton tomography and fluorescence lifetime imaging. Exp Dermatol. 2022 Nov;31(11):1712-1719. doi: 10.1111/exd.14646. Epub 2022 Jul 25. | |
| 41137607 | Derived | Nguyen L, Mess C, Huck V, Schneider SW, Herberger K. Intravital Visualization of Tattoo Particles After Picosecond Laser Treatment. Skin Res Technol. 2025 Oct;31(10):e70283. doi: 10.1111/srt.70283. |
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| ID | Term |
|---|---|
| D014894 | Weights and Measures |
| ID | Term |
|---|---|
| D008919 | Investigative Techniques |
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| nanosecond laser treatment + measurement with a multiphoton tomography system | Other | Patients with unwanted tattoos who plan a laser treatment will be recruited for measurements using a multiphoton-tomography system. These are scheduled 6 weeks and 12 weeks post-treatment. |
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