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15-20 trained bodybuilding athletes were divided into caffeine gum trial (CAF) and placebo trial (PL) with a randomized, double-blind study design. The participants chewing either caffeine Gum (CAF trial, containing 5 mg/kg of caffeine) or placebo gum (PL) for 10 minutes. After rested for 15 minutes, Participants used the bicycle to adjust the pedal resistance and speed according to their own feelings until they were dehydrated to 2% of their original body weight.
The purpose of this study was to investigate the effect of caffeinated chewing gum on dehydration ability in bodybuilding athletes. Methods: 15-20 trained bodybuilding athletes were divided into caffeine gum trial (CAF) and placebo trial (PL) with a randomized, double-blind study design. The participants chewing either caffeine Gum (CAF trial, containing 5 mg/kg of caffeine) or placebo gum (PL) for 10 minutes. After rested for 15 minutes, Participants used the bicycle to adjust the pedal resistance and speed according to their own feelings until they were dehydrated to 2% of their original body weight. Record time from exercise to completion of dehydration, heart rate, HRV, energy expenditure, fat oxidation rate and carbohydrate oxidation rate.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| caffeine gum | Experimental | Chewing caffeine Gum (CAF trial, containing 5 mg/kg of caffeine) for 10 minutes before test. |
|
| placebo | Placebo Comparator | Chewing placebo gum (without caffeine) for 10 minutes before test. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| caffeine | Dietary Supplement | The participants chewed either caffeine gum (5 mg/kg for 10 minutes per chew) or a placebo (10 minutes per chew, using regular gum). |
|
| Measure | Description | Time Frame |
|---|---|---|
| dehydration speed | The participants start dehydration until dehydrated to 2% of their original body weight. | 15 minutes after intervention |
| Measure | Description | Time Frame |
|---|---|---|
| energy expenditure | The energy expenditure during dehydration | 15 minutes after intervention |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| ChihHui Chiu, PhD | National Taiwan University of Sport | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| National Taiwan University of Sport | Taichung | 404 | Taiwan |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 40287780 | Derived | Liu HS, Okada T, Mitsuya H, Hsieh MH, Hou CW, Chang CC, Chiu CH. Effects of caffeinated chewing gum-induced sympathetic activation and diuretic effect on the rapid rate of weight loss in bodybuilders: a double-blind crossover study. BMC Sports Sci Med Rehabil. 2025 Apr 26;17(1):98. doi: 10.1186/s13102-025-01144-z. |
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Only participant number and experimental data are provided.
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot | Yes | No | No | Study Protocol | May 23, 2024 | May 24, 2024 | Prot_000.pdf |
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| ID | Term |
|---|---|
| D002110 | Caffeine |
| ID | Term |
|---|---|
| D014970 | Xanthines |
| D000470 | Alkaloids |
| D006571 | Heterocyclic Compounds |
| D011688 | Purinones |
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The participants were divided into caffeine gum trial (CAF) and placebo trial (PL) with a randomized, double-blind study design.
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Using placebo chewing gum
|
| D011687 |
| Purines |
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |