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This study is planned to reveal the microbiological agents and drug sensitivities to these agents in patients diagnosed with chronic suppurative otitis media who complain of ear discharge.
Patients with complaints of ear discharge and who were diagnosed with chronic suppurative otitis media will be included in the study. Patients will be divided into two groups: CSOM with cholesteatoma and CSOM without cholesteatoma. One hundred ten patients from each group will be included in the study. After a comprehensive medical history is taken for each patient, the patient's external auditory canal will be cleaned with sterile aspirators. A sterile culture will be taken from the discharge of the ear and sent to microbiology. With the data obtained from microbiological examination, pathogens will be classified as gram-positive, gram-negative, anaerobic, and fungal and examined according to monomicrobial and polymicrobial growth. Antibiotic susceptibility tests will be conducted to determine the effectiveness of antibiotics against the bacteria causing the infection.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Chronic suppurative otitis media with cholesteatoma (Chole) | Patients who applied to Selçuk University Faculty of Medicine Hospital, Department of Ear, Nose and Throat Diseases & Head and Neck Surgery with complaints of ear discharge and were diagnosed with chronic suppurative otitis media with cholesteatoma were included in the study. |
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| Chronic suppurative otitis media without cholesteatoma (CSOM) | The study included patients who applied to Selçuk University Faculty of Medicine Hospital, Department of Ear, Nose and Throat Diseases & Head and Neck Surgery, with complaints of ear discharge and were diagnosed with chronic suppurative otitis media without cholesteatoma. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Microbiological culture | Diagnostic Test | Samples taken from chronic suppurative otitis media patients in the Medical Microbiology Laboratory of Selçuk University Faculty of Medicine will be planted in 5% sheep blood Columbia agar, eosin methylene blue agar and saboraud dextrose agar, and the media will be incubated at 37oC for 24-48 hours. Growing bacteria and fungi were examined using traditional methods [Gram staining, catalase test, coagulase test, bacitracin disk, PYR test (L-pyrrolidonyl-β-naphthylamide), oxidase test, IMViC test, lactophenol cotton blue, etc.] and VITEK 2 (bioMerieux, France). |
| Measure | Description | Time Frame |
|---|---|---|
| Microbiology of chronic suppurative otitis media | Microbiology in patients diagnosed with chronic suppurative otitis media with and without cholesteatoma | 2024-2026 (24 months) |
| Measure | Description | Time Frame |
|---|---|---|
| Antibiotic susceptibility in chronic suppurative otitis media | Investigation of antibiotic susceptibility and resistance in patients diagnosed with chronic suppurative otitis media with and without cholesteatoma. | 2024-2026 (24 months) |
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Inclusion Criteria:
Exclusion Criteria:
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The study will include patients who applied to Selçuk University Faculty of Medicine Hospital, Department of Ear, Nose and Throat Diseases & Head and Neck Surgery, with complaints of ear discharge and were diagnosed with chronic suppurative otitis media.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Burcu Tuğba Aldora | Contact | +905437608870 | etikselcuk@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Bulent Ulusoy, MD | Selcuk University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bulent ULUSOY | Konya | Selcuklu | 42100 | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37727177 | Background | Khairkar M, Deshmukh P, Maity H, Deotale V. Chronic Suppurative Otitis Media: A Comprehensive Review of Epidemiology, Pathogenesis, Microbiology, and Complications. Cureus. 2023 Aug 18;15(8):e43729. doi: 10.7759/cureus.43729. eCollection 2023 Aug. | |
| 16198004 | Background | Verhoeff M, van der Veen EL, Rovers MM, Sanders EA, Schilder AG. Chronic suppurative otitis media: a review. Int J Pediatr Otorhinolaryngol. 2006 Jan;70(1):1-12. doi: 10.1016/j.ijporl.2005.08.021. Epub 2005 Sep 27. |
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| ID | Term |
|---|---|
| D010033 | Otitis Media |
| D002781 | Cholesteatoma |
| D003141 | Communicable Diseases |
| ID | Term |
|---|---|
| D010031 | Otitis |
| D004427 | Ear Diseases |
| D010038 | Otorhinolaryngologic Diseases |
| D007642 | Keratosis |
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Culture samples taken from the ears of patients with chronic suppurative otitis media with cholesteatoma and chronic suppurative otitis media without cholesteatom.
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| Selcuk University | Konya | Selcuklu | 42100 | Turkey (Türkiye) |
| D012871 |
| Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D007239 | Infections |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |