Paradoxical Reactions of Remimazolam in Pediatric Painless Gastrointestinal Endoscopy

Paradoxical Reactions of Remimazolam in Pediatric Painless Gastrointestinal Endoscopy: Incidence, Characters and Its Impact on Prognostic Outcomes-- a Randomized, Controlled Clinical Trial

Exploring the effect of remimazolam dose on paradoxical reactions in pediatric painless gastrointestinal endoscopy.

Exploring the effect of remimazolam dose on paradoxical reactions and sedation in pediatric painless gastrointestinal endoscopy, observing the performance and duration of paradoxical reactions, and analyze the factors.

Inclusion Criteria:

• Age 1-12 years old
• ASA I-II level
• Sign an informed consent form

Exclusion Criteria:

• Developmental delay or neurological and psychiatric disorders
• Severe malnutrition or severe obesity
• High risk of stomach fullness and reflux aspiration
• Allergic to benzodiazepines and opioids
• Those who have taken sedative, analgesic, or antidepressant drugs within 24hours
• Severe sleep apnea
• Abnormal liver and kidney function
• Recently participated in other clinical studies