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In this observational cohort study data on all patients undergoing liver transplantation after hypothermic oxygenated machine perfusion at Medical University of Vienna will be prospectively recorded. Investigation of short- and long-term outcome in this cohort will be conducted.
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| Measure | Description | Time Frame |
|---|---|---|
| Incidence of ischemic-type biliary lesions | Non-anastomotic stenosis, post-transplant cholangiopathy | Within one year after liver transplantation |
| Measure | Description | Time Frame |
|---|---|---|
| Rate of early allograft dysfunction | Deviation of bilirubin, transaminases or international normalised ratio | Evaluated within the first 7 postoperative days |
| Rate of primary non-function | Evaluated in the immediate postoperative period, specifically within the first postoperative week |
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Inclusion Criteria:
Exclusion Criteria:
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Patients listed for and undergoing liver transplantation using a liver graft which was subjected to hypothermic oxygenated machine perfusion
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| David Pereyra, MD, PhD | Contact | +4314040056210 | david.pereyra@muv.ac.at | |
| Jule Dingfelder, MD | Contact | +4314040056210 | jule.dingfelder@muv.ac.at |
| Name | Affiliation | Role |
|---|---|---|
| Gabriela A Berlakovich, Prof, MD | Medical University of Vienna, Division of Transplantation | Study Chair |
| Georg Györi, MD | Medical University of Vienna, Division of Transplantation | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Medical University of Vienna | Recruiting | Vienna | 1090 | Austria |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39422535 | Derived | Pereyra D, Dingfelder J, Riha M, Kacar S, Rauter L, Becker N, Saffarian Zadeh T, Tortopis C, Starlinger P, Ristl R, Silberhumer G, Salat A, Soliman T, Berlakovich G, Gyoeri G. Dual hypothermic oxygenated machine perfusion of the liver reduces post-transplant biliary complications: a retrospective cohort study. Int J Surg. 2024 Dec 1;110(12):7909-7918. doi: 10.1097/JS9.0000000000002115. |
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data available upon reasonable request and in accordance with appropriate data sharing agreements
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| ID | Term |
|---|---|
| D058625 | End Stage Liver Disease |
| D006528 | Carcinoma, Hepatocellular |
| ID | Term |
|---|---|
| D017093 | Liver Failure |
| D048550 | Hepatic Insufficiency |
| D008107 | Liver Diseases |
| D004066 | Digestive System Diseases |
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| Incidence of re-transplantation | Evaluated in the immediate postoperative period, specifically within the first postoperative week |
| D000230 |
| Adenocarcinoma |
| D002277 | Carcinoma |
| D009375 | Neoplasms, Glandular and Epithelial |
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
| D008113 | Liver Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |