A Randomized, Double-blind, Multi-center, Phase III study to evaluate the efficacy and safety of the AJU-C52 compared with the combination of C52R1M in patients with essential Hypertension Patients who have inappropriately controlled on C52R1L treament

Inclusion Criteria:

• Adults aged ≤19 years.
• Those who voluntarily signed the informed consent to participate in this study.
• A patient diagnosed with essential hypertension or Patients taking hypertension medication
• Those who are eligible for adequate blood pressure criteria during screening tests: Naïve patient-160 mmHg≤MSSBP<200 mmHg and MSDBP<110 mmHg/Patients taking hypertension medication-140 mmHg≤MSSBP<200 mmHg and MSDBP<110 mmHg

Exclusion Criteria:

• At the screening visit (Visit 1), patients had 3 blood pressure measurements in the arm with the higher average MSSBP, those whose maximum and minimum blood pressure differences are MSSBP 20 mmHg and MSDBP 10 mmHg
• Secondary hypertension patients or those with a history of suspected secondary hypertension
• Cardiovascular/cerebrovascular disease
• Those with a history of malignant tumor within 5 years