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| Name | Class |
|---|---|
| Xinxiang Central Hospital | OTHER |
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The equivalent dose of sufentanil and afentanil combined with laryngeal mask was used for complex bronchoscopy to observe the intraoperative effect and the influence on the recovery of patients
Afentanil is a powerful, fast-acting narcotic analgesic, which can effectively inhibit intubation reflex. Compared with sufentanil, it has a short half-life and is safer, and can be used as the first choice for short surgical analgesics. In this study, by comparing the use of equivalent dose sufentanil and afentanil combined with laryngeal mask for complex bronchoscopy, the intraoperative analgesic effect and the influence on the recovery of patients were observed, and a better anesthesia scheme was provided for tracheoscopy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Sufentanil group | Experimental | The dose of sufentanil group is 0.2μg/kg |
|
| Alfentanil | Experimental | The dose of aifentanil group is 10μg/kg |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Alfentanil | Drug | alfentanil 10ug/kg is used for anesthesia induction |
|
| Measure | Description | Time Frame |
|---|---|---|
| time of Recovery | the time from the end of surgery to awake of patient | 1day |
| Measure | Description | Time Frame |
|---|---|---|
| Time records | Anesthesia time, induction time, surgical time, awakening time and recovery time | 1 day |
| dose of drugs | The total amount of sedative and analgesic drugs used. |
| Measure | Description | Time Frame |
|---|---|---|
| rate of Postoperative adverse reaction | Airway obstruction, hypoxemia, apnea, laryngeal spasm, bronchospasm, cough, postoperative nausea and vomiting, postoperative pain (VAS score), hypotension, bradycardia, dizziness | 1 day |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| aijun xu, Dr | Tongji Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Aijun Xu | Hubei | Wuhan | 430000 | China |
You can request it from the main researcher.
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| ID | Term |
|---|---|
| D015760 | Alfentanil |
| D017409 | Sufentanil |
| ID | Term |
|---|---|
| D005283 | Fentanyl |
| D010880 | Piperidines |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
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| 1 day |
| rate of respiratory suppression incidence | Respiratory frequency<8 times/min or SP02<90% | 1 day |
| rate of Incidence of Treatment-Emergent Adverse Events | Intraoperative blood pressure and heart rate changes: record the patient's intraoperative blood pressure, heart rate, and the use of related vasoactive drugs; Postoperative adverse reactions: such as hypertension, hypotension, tachycardia, gastrointestinal symptoms, postoperative restlessness, etc | 1day |