Most intracranial aneurysms are found accidentally in neurovascular imaging. And these inspection methods are limited by the problems of instrument fixation, radiation, time-consuming, contrast agent toxicity and so on. At present, blood test is an ideal alternative method for early diagnosis. Compared with imaging examination, it is economical, general screening and convenient. Blood test is simple to operate, easy to be accepted by patients, and less invasive. Early screening of aneurysms can be performed.

Inclusion Criteria:

• Age 35-75
• Individuals with normal cognitive and communication abilities
• No serious complications, such as uncontrolled hypertension, diabetes or other chronic diseases that may affect the test results.
• Basic blood test is normal or close to normal range.

Exclusion Criteria:

• Pregnancy
• Severe heart disease, renal insufficiency, liver dysfunction and other major diseases.
• In the past 6 months, there were strokes, or other types of intracranial tumors, infections and other diseases that may affect the screening results.
• There are metal implants, including dentures, pacemakers, etc.
• Using or recently used drugs that may affect blood biomarkers ( such as anticoagulant drugs, immunosuppressive agents, etc. ).
• There are serious mental illness or cognitive dysfunction, such as claustrophobia, unable to cooperate with the completion of the test.
• It is currently participating in other clinical trials or has participated in other clinical trials in the past 3 months.