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| Name | Class |
|---|---|
| Ministry of Higher Education, Malaysia | OTHER |
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The goal of this interventional study is to develop and assess the effectiveness of a peer-led digital health program (MYCardio-PEER) for primary prevention of cardiovascular disease (CVD) in a low-income community at-risk of CVD.
The main questions it aims to answer are:
Participants will attend the 8-weeks MYCardio-PEER program with their peer leaders, supplemented with face-to-face components. Participants will then be followed up for another 12 weeks, during which peer leaders and researchers will have minimal contact with the participants. Participants who have been allocated into the control group will receive printed documents with standard tips on dietary and lifestyle management for CVD, where they will be encouraged to maintain regular calorie intake and expenditure and perform regular exercise.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intervention | Experimental | Participants will attend the 8-weeks MYCardio-PEER program with their peer leaders, supplemented with face-to-face components. |
|
| Control | No Intervention | Participants will receive printed documents with standard tips on dietary and lifestyle management for CVD. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| MYCardio-PEER | Behavioral | MYCardio-PEER participants will attend an 8-weeks intervention program delivered over the social networking application. Bite-sized videos and infographic posters on healthy diet and lifestyle for primary prevention of CVD will be delivered weekly, supplemented by interactive peer-group activities to encourage behavior change. |
| Measure | Description | Time Frame |
|---|---|---|
| Framingham Risk Score for Cardiovascular Disease Risk | The score is based on a person's age, sex, blood pressure, cholesterol levels, smoking status, and diabetes status. The calculated score will be converted into 10-year risk percentage whereby the higher the percentage means higher cardiovascular disease risk. | 20 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Blood pressure | The blood pressure will be measured in mmHg. Blood pressure more than 140/90 mmHg is considered high blood pressure. | 20 weeks |
| Total cholesterol level | Total cholesterol will be measured in mmol/L. Total cholesterol more than 5.2 mmol/L is considered high. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Amutha Ramadas, PhD | Monash University Malaysia | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Monash University | Subang Jaya | Selangor | 47500 | Malaysia |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 42002507 | Derived | Lim GP, Appalasamy JR, Ahmad B, Quek KF, Ramadas A. Cardiovascular risk reduction through a peer-led digital health lifestyle intervention in a low-income community: outcomes from the MYCardio-PEER program. Nutr Metab Cardiovasc Dis. 2026 Apr 5:104723. doi: 10.1016/j.numecd.2026.104723. Online ahead of print. | |
| 41222971 | Derived |
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| ID | Term |
|---|---|
| D002318 | Cardiovascular Diseases |
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| 20 weeks |
| High-density lipoprotein cholesterol (HDL-C) level | High-density lipoprotein cholesterol (HDL-C) will be measured in mmol/L. The healthy cut-off points of HDL-C in male is more than 1.0 mmol/L and in female more than 1.3 mmol/L. | 20 weeks |
| Low-density lipoprotein cholesterol (LDL-C) level | Low-density lipoprotein cholesterol (LDL-C) will be measured in mmol/L. The healthy cut-off point of LDL-C is less than 2.6 mmol/L. | 20 weeks |
| Triglycerides level | Triglycerides level will be measured in mmol/L. The healthy cut-off point of triglycerides level is less than 1.7 mmol/L. | 20 weeks |
| Fasting blood glucose level | Fasting blood glucose level will be measured in mmol/L. The healthy cut-off point of fasting blood glucose level is less than 6.1 mmol/L. | 20 weeks |
| Body weight | Body weight will be assessed in kilograms. | 20 weeks |
| Body height | Body height will be assessed in meters. | Baseline |
| Body mass index | Body mass index (BMI) is derived from body weight in kilograms (kg) and body height in meters (m). BMI is expressed as kg/m^2. | 20 weeks |
| Waist circumference | Waist circumference will be assessed in centimeters (cm). The healthy cut-off point of waist circumference for male is less than or equal to 90cm and for female less than or equal to 80cm. | 20 weeks |
| Attitude and Beliefs about Cardiovascular Risk | Attitude and Beliefs about Cardiovascular Risk will be assessed using the Attitude and Beliefs about Cardiovascular Risk - Malay questionnaire. The overall score was calculated from all item scores by the domains. The higher the score, the higher the awareness and the readiness to change the behavior. | 20 weeks |
| Physical activity level | The physical activity level will be assessed using the International Physical Activity Questionnaire. The intensity of self-reported physical activity lasting at least 10 minutes per bout was measured in metabolic equivalent (MET). The accumulated MET-minutes per week will be calculated to categorize into low, moderate (at least 600 MET-minutes per week) or high physical activity level (at least 3000 MET-minutes per week). | 20 weeks |
| Medication Understanding and Taking Self-Efficacy | The Medication Understanding and Taking Self-Efficacy will be assessed using the Medication Understanding and Taking Self-Efficacy scale. The scores ranged from 8 to 32, with higher scores indicating greater levels of medication understanding. | 20 weeks |
| Dietary intakes | The usual dietary intakes will be assessed using the short food frequency questionnaire. It provides details on daily intake of food groups. | 20 weeks |
| Nutrient intakes | Nutrient intakes will be assessed using the 2-day 24-hour diet recalls. The participants will be asked about all details of the foods and beverages consumed in the past 24 hours, including the types of food, cooking methods, estimated portion size and brands. Nutrient intakes from 24-hour dietary recalls will be analyzed with Nutritionist Pro software (Axxya Systems, USA) to yield total energy, macronutrient and micronutrient intakes. | 20 weeks |
| Stress level | The stress level will be assessed using the Perceived Stress Scale (PSS). Individual scores on the PSS can range from 0 to 40 with higher scores indicating higher perceived stress.
| 20 weeks |
| Smoking habit | Participants will be asked if they are non-smoker, past smoker or current smoker; how long have you been smoking; and how many cigarettes did/do you smoke per day? | 20 weeks |
| Alcohol consumption | Participants will be asked if they are non-drinker, past drinker or current drinker; how long (years) have you been consuming alcohol? | 20 weeks |
| Lim GP, Appalasamy JR, Ahmad B, Quek KF, Ramadas A. Peer-Led Digital Health Lifestyle Intervention in a Low-Income Community at Risk for Cardiovascular Disease (MYCardio-PEER): Mixed Methods Development and Process Evaluation Study. J Med Internet Res. 2025 Nov 12;27:e77063. doi: 10.2196/77063. |
| 40025749 | Derived | Lim GP, Appalasamy JR, Ahmad B, Quek KF, Shaharuddin S, Ramadas A. Peer-led digital health lifestyle intervention for a low-income community at risk for cardiovascular diseases (MYCardio-PEER): a quasi-experimental study protocol. Prim Health Care Res Dev. 2025 Mar 3;26:e20. doi: 10.1017/S1463423625000192. |