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| Name | Class |
|---|---|
| Wageningen University and Research | OTHER |
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Sleeve gastrectomy (SG) increases gastrointestinal motility, which influences feelings of fullness and satiety. By understanding the differences in gastric emptying (GE) between patients with sufficient weight loss (Total weight loss [TWL] > 35%) and insufficient weight loss (TWL < 25%), better insight in the aetiology of weight loss after sleeve gastrectomy may be obtained. GE will be measured with scintigraphy and MRI.
Sleeve gastrectomy (SG) increases gastrointestinal motility, which influences feelings of fullness and satiety. Patients' weight loss response on SG varies widely and is difficult to predict. By understanding the differences in gastric emptying (GE) between patients with sufficient weight loss (Total weight loss [TWL] > 35%) and insufficient weight loss (TWL < 25%), better insight in the aetiology of weight loss after sleeve gastrectomy may be obtained. GE will be measured with scintigraphy and MRI. MRI is a non-invasive imaging method which provides more detailed images of the SG compared to the conventionally used scintigraphy scans.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Poor weight loss group | Women aged between 20 and 55 years who underwent sleeve gastrectomy as primary procedure with TWL < 25% |
| |
| Successful weight loss group | Women aged between 20 and 55 years who underwent sleeve gastrectomy as primary procedure with TWL > 35% |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| MRI and scintigraphy | Other | Gastric emptying measured with MRI and scintigraphy |
|
| Measure | Description | Time Frame |
|---|---|---|
| Gastric emptying compared between patients with poor and successful weight loss | Gastric emptying (T1/2 [min] and retention [%/min]) | 2-3 years |
| Gastric emptying compared between measured with MRI and scintigraphy | Gastric emptying (T1/2 [min] and retention [%/min]) | 2-3 years |
| Measure | Description | Time Frame |
|---|---|---|
| Sleeve characteristics compared between patients with successful and unsuccessful (poor) weight loss | Volume (sleeve size [mL] and gastric acid [mL]) | 2-3 years |
| to assess the association between gastric emptying rate and gastric sleeve characteristics in each group |
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Inclusion Criteria:
Exclusion Criteria:
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Women after sleeve gastrectomy with either good or poor weight loss
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Rijnstate Hospital | Arnhem | Gelderland | 6815AD | Netherlands |
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| ID | Term |
|---|---|
| D009682 | Magnetic Resonance Spectroscopy |
| ID | Term |
|---|---|
| D013057 | Spectrum Analysis |
| D002623 | Chemistry Techniques, Analytical |
| D008919 | Investigative Techniques |
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association between outcome 1, 2 and 3 |
| 2-3 years |
| to compare subjective ratings of gastric fullness and wellbeing between patients with successful and unsuccessful weight loss | questionnaires (VAS-scale, MAIA, HADS, EBBS, Power of food scale, and Food tolerance test) | 2-3 years |