The aim of this observational register study is to establish a registry that completely records and compiles the data from routinely performed technical examinations (navigated transcranial magnetic stimulation, intraoperative neuromonitoring and stimulation, MRI imaging including tractography and connectome) and clinical tests over time (pre-, intra- and postoperative, under adjuvant therapy, as part of follow-up care) of patients with intracranial masses and lesions.

Inclusion Criteria:

• Intracranial lesion
• Age ≥ 18 years
• Written consent to participate in the study

Exclusion Criteria:

• Age < 18 years
• Patients not able to give consent
• Patients with intracranial ferromagnetic metal implants
• Patients with implanted electronic devices

Patients with brain masses/lesions (especially tumors (cerebral and non-cerebral, inflammation (infectious and non-infectious), vascular pathologies)

For selected subgroups, data sharing is possible depending on data safety regulations